Evidence map›Paper›PMID 35659087›Full record

ArticleInfectious diseases of poverty2022

Key immunity characteristics of diverse stages of brucellosis in rural population from Inner Mongolia, China.

Yongzhang Zhu, Li Shi, Yige Zeng, Dongri Piao, Yingbo Xie, Juan Du, Meng Gao, Wei Gao, Junli Tian, Jun Yue and 4 more

Open access · goldAbstract read
In one paragraph

Article in Infectious diseases of poverty, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Frontiers in cellular and infection microbiology · 2024
    Review
  10. Analysis of Clinical Characteristics and Blood Cell in Adult Patients with Brucella Bloodstream Infection of Different Blood Groups.Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 1 country.

Yongzhang Zhu *School of Global Health, Chinese Center for Tropical Diseases Research, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Li Shi *Department of Immunogenetics, Institute of Medical Biology, Chinese Academy of Medical Sciences & Peking Union Medical College, Kunming, China.
Yige Zeng *Department of Biological Science, Xi'an Jiaotong-Liverpool University, Suzhou, China.
Dongri PiaoState Key Laboratory for Infectious Disease Prevention and Control, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
Yingbo XieBaotou Municipal Center for Disease Control and Prevention, Baotou, Inner Mongolia, China.
Juan DuBaotou Municipal Center for Disease Control and Prevention, Baotou, Inner Mongolia, China.
Meng GaoBaotou Municipal Center for Disease Control and Prevention, Baotou, Inner Mongolia, China.
Wei GaoBaotou Municipal Center for Disease Control and Prevention, Baotou, Inner Mongolia, China.
Junli TianBaotou Municipal Center for Disease Control and Prevention, Baotou, Inner Mongolia, China.
Jun YueBaotou Municipal Center for Disease Control and Prevention, Baotou, Inner Mongolia, China.
Min LiSchool of Global Health, Chinese Center for Tropical Diseases Research, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
XiaoKui GuoSchool of Global Health, Chinese Center for Tropical Diseases Research, Shanghai Jiao Tong University School of Medicine, Shanghai, China. microbiology@sjtu.edu.cn.
Yufeng YaoDepartment of Immunogenetics, Institute of Medical Biology, Chinese Academy of Medical Sciences & Peking Union Medical College, Kunming, China. leoyyf@gmail.com.
YaoXia KangBaotou Municipal Center for Disease Control and Prevention, Baotou, Inner Mongolia, China. kyxaa@126.com.
Shanghai Jiao Tong University · CNChinese Academy of Medical Sciences & Peking Union Medical College · CNInner Mongolia Comprehensive Disease Prevention and Control Center · CNNational Institute for Communicable Disease Control and Prevention · CNXi’an Jiaotong-Liverpool University · CN

Funding

National Natural Science Foundation of China 81460319National Natural Science Foundation of China 82060383Natural Science Foundation of Inner Mongolia 2019MS08209
6 · The paper itself

Abstract

backgroundBrucellosis poses a serious threat to human and animal health, particularly in developing countries such as China. The Inner Mongolia Autonomous Region is one of the most severely brucellosis-endemic provinces in China. Currently, the host immune responses functioning to control Brucella infection and development remain poorly understood. The aim of this study is to further clarify the key immunity characteristics of diverse stages of brucellosis in Inner Mongolia.

methodsWe collected a total of 733 blood samples from acute (n = 137), chronic (n = 316), inapparent (n = 35), recovery (n = 99), and healthy (n = 146) groups from the rural community of Inner Mongolia between 2014 and 2015. The proportions of CD4

resultsOur results revealed that the proportions of CD4

conclusionsTwo key factors (CD8

Indexed as

BrucellosisCD8-Positive T-LymphocytesAnimalsChinaHumansRural PopulationToll-Like Receptor 4Toll-Like Receptor 4CD4+ T cellsCD8+ T cellsHuman brucellosisTh cellsTLR2TLR4

Identifiers

PMID35659087
PMCPMC9167523
OpenAlexW4281610777

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.