ArticleHealth and quality of life outcomes2022
Adaptation and validation of a German version of the Multimorbidity Treatment Burden Questionnaire.
Article in Health and quality of life outcomes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 22 citations in OpenAlex.
- The Treatment-Related Burnout Scale for Rheumatic Diseases: Development and Preliminary Validation.Clinical rheumatology · 2026Article
- Adaptation and psychometric validation of treatment burden questionnaire for caregivers of older adults with diabetes and dementia.Aging & mental health · 2026Article
- Development and validation of a Japanese version of the multimorbidity treatment burden questionnaire.Scientific reports · 2025Article
- The complex relationship between treatment burden of multimorbidity and self-care in multimorbid patients with hypertension.BMC primary care · 2025Article
- Measurement of treatment burden in patients with multimorbidity in the Netherlands: translation and validation of the Multimorbidity Treatment Burden Questionnaire (NL-MTBQ).Family practice · 2024Article
- Treatment burden in multimorbidity: an integrative review.BMC primary care · 2024Review
- Further development and validation of the Multimorbidity Treatment Burden Questionnaire (MTBQ).BMJ open · 2024Article
- Validation of the Lithuanian multimorbidity treatment burden questionnaire (MTBQ) and its association with primary care patient characteristics.The European journal of general practice · 2023Article
- Treatment burden and health-related quality of life of patients with multimorbidity: a cross-sectional study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2023Article
- Associations between treatment burden, socio-demographics, clinical factors and use of medicines in adults with polypharmacy: A cross-sectional study.Journal of multimorbidity and comorbidityArticle
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundPatients with multiple long-term conditions often face a variety of challenges arising from the requirements of their health care. Knowledge of perceived treatment burden is crucial for optimizing treatment. In this study, we aimed to create a German version of the Multimorbidity Treatment Burden Questionnaire (MTBQ) and to evaluate its validity.
methodsThe steps to translate the MTBQ included forward/back translation, cognitive interviews (n = 6) and a pilot test (n = 7). Psychometric properties of the scale were assessed in a cross-sectional survey with primary care patients aged 65 and older with at least 3 long-term conditions (n = 344). We examined the distribution of responses, dimensionality, internal reliability and construct validity.
resultsCognitive interviewing and piloting led to minor modifications and showed overall good face validity and acceptability. As expected, we observed a positively skewed response distribution for all items. Reliability was acceptable with McDonald's omega = 0.71. Factor analysis suggested one common factor while model fit indices were inconclusive. Predefined hypotheses regarding the construct validity were supported by negative associations between treatment burden and health-related quality of life, self-rated health, social support, patient activation and medication adherence, and positive associations between treatment burden and number of comorbidities. Treatment burden was found to be higher in female participants (Mdn
conclusionsThe German MTBQ exhibited good psychometric properties and can be used to assess the perceived treatment burden of patients with multimorbidity.
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