Evidence map›Paper›PMID 35658680›Full record

ArticlePhilosophical transactions. Series A, Mathematical, physical, and engineering sciences2022

An affordable implantable vagus nerve stimulator system for use in animal research.

Ángel Canal-Alonso, Roberto Casado-Vara, Orlando Castellano, Jorge Herrera-Santos, Jaime Gonçalves, Sergio Màrquez-Sànchez, Jesús María Gonçalves, Juan Manuel Corchado

Open access · hybridAbstract read
In one paragraph

Article in Philosophical transactions. Series A, Mathematical, physical, and engineering sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
  3. Preface to 'Advanced neurotechnologies: translating innovation for health and well-being'.Philosophical transactions. Series A, Mathematical, physical, and engineering sciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Ángel Canal-AlonsoBioinformatics, Intelligent Systems and Educational Technology (BISITE) Research Group, Salamanca, Spain.ORCID 0000-0002-4254-5944
Roberto Casado-VaraBioinformatics, Intelligent Systems and Educational Technology (BISITE) Research Group, Salamanca, Spain.
Orlando CastellanoInstitute for Biomedical Research of Salamanca (IBSAL), Salamanca, Spain.
Jorge Herrera-SantosBioinformatics, Intelligent Systems and Educational Technology (BISITE) Research Group, Salamanca, Spain.
Jaime GonçalvesInstitute for Biomedical Research of Salamanca (IBSAL), Salamanca, Spain.
Sergio Màrquez-SànchezBioinformatics, Intelligent Systems and Educational Technology (BISITE) Research Group, Salamanca, Spain.
Jesús María GonçalvesInstitute for Biomedical Research of Salamanca (IBSAL), Salamanca, Spain.
Juan Manuel CorchadoBioinformatics, Intelligent Systems and Educational Technology (BISITE) Research Group, Salamanca, Spain.
Universidad de Salamanca · ESInstituto de Investigación Biomédica de Salamanca · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this research, a vagus nerve stimulator has been developed and miniaturized for use in epilepsy research. The board contains all the components necessary for its operation during the standard duration of the experiments, being possible to control it once implanted and even being able to reuse it. The VNS system has been designed for rodents since the VNS devices available for human are not only too large for laboratory animals, but also too expensive. With this solution the expenditure on materials made by laboratories is greatly reduced and bioethical considerations were kept in mind. The system was validated in hamsters. This article is part of the theme issue 'Advanced neurotechnologies: translating innovation for health and well-being'.

Indexed as

Animal ExperimentationEpilepsyVagus Nerve StimulationAnimalsTreatment OutcomeVagus Nerveepilepsyimplantable devicesneuromodulation

Identifiers

PMID35658680
PMCPMC9168444
OpenAlexW4281725209

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.