Evidence map›Paper›PMID 35658577›Full record

ArticleMicrobiology spectrum2022

High Osmotic Stress Increases OmpK36 Expression through the Regulation of KbvR to Decrease the Antimicrobial Resistance of Klebsiella pneumoniae.

Meng Wang, Yujiao Tian, Li Xu, Fusheng Zhang, Huigai Lu, Moran Li, Bei Li

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.1field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 17 citations in OpenAlex.

  1. RecCVirulence · 2026
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  2. Hypermucoviscosity inJournal of bacteriology · 2026
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  4. Antibiotic Resistance inAntibiotics (Basel, Switzerland) · 2026
    Review
  5. Investigating the Effect of Xylitol onInternational journal of microbiology · 2026
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  7. Aerosolization AffectsMicroorganisms · 2025
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  8. Development of a Promising Bivalent Vaccine AgainstExploration (Beijing, China) · 2025
    Article
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  12. Article
  13. Article
  14. Article
  15. Harnessing regulatory networks in Actinobacteria for natural product discovery.Journal of industrial microbiology & biotechnology · 2024
    Review
  16. RfaH contributes to maximal colonization and full virulence of hypervirulentFrontiers in cellular and infection microbiology · 2024
    Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Meng Wang *School of Basic Medicine, Hubei University of Medicinegrid.443573.2, Shiyan, Hubei, People's Republic of China.
Yujiao Tian *School of Basic Medicine, Hubei University of Medicinegrid.443573.2, Shiyan, Hubei, People's Republic of China.
Li XuBiomedical Research Institute, Hubei University of Medicinegrid.443573.2, Shiyan, Hubei, People's Republic of China.
Fusheng ZhangSchool of Basic Medicine, Hubei University of Medicinegrid.443573.2, Shiyan, Hubei, People's Republic of China.
Huigai LuSchool of Basic Medicine, Hubei University of Medicinegrid.443573.2, Shiyan, Hubei, People's Republic of China.
Moran LiSchool of Basic Medicine, Hubei University of Medicinegrid.443573.2, Shiyan, Hubei, People's Republic of China.
Bei LiSchool of Basic Medicine, Hubei University of Medicinegrid.443573.2, Shiyan, Hubei, People's Republic of China.ORCID 0000-0002-4766-5005
Hubei University of Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Klebsiella pneumoniae is a pathogen known for its high frequency of antimicrobial resistance. Responses to various environmental stresses during its life can influence the resistance to antibiotics. Here, we demonstrate the role and mechanism of KbvR regulator in the response to environmental osmotic stress and in the effect of osmotic stress on antimicrobial resistance. The

Indexed as

Klebsiella InfectionsKlebsiella pneumoniaeAnti-Bacterial AgentsBacterial Proteinsbeta-Lactamasesbeta-LactamsDrug Resistance, BacterialHumansMicrobial Sensitivity TestsOsmotic PressurePorinsAnti-Bacterial AgentsBacterial Proteinsbeta-Lactamasesbeta-LactamsPorinsantimicrobial resistanceKbvRKlebsiella pneumoniaeOmpK36osmotic stress

Identifiers

PMID35658577
PMCPMC9241633
OpenAlexW4281787967

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.