Evidence map›Paper›PMID 35658044›Full record

ArticleScience advances2022

Single-nucleosome imaging reveals steady-state motion of interphase chromatin in living human cells.

Shiori Iida, Soya Shinkai, Yuji Itoh, Sachiko Tamura, Masato T Kanemaki, Shuichi Onami, Kazuhiro Maeshima

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Science advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
4.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 60 citations in OpenAlex.

  1. Article
  2. Article
  3. Integrative modeling of the genome structure and dynamics in fission yeast.Proceedings of the National Academy of Sciences of the United States of America · 2026
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  16. Mitochondria power the nucleus under pressure.Mechanobiology in medicine · 2025
    Article
  17. The shifting paradigm of chromatin structure: from the 30-nm chromatin fiber to liquid-like organization.Proceedings of the Japan Academy. Series B, Physical and biological sciences · 2025
    Review
  18. In-cell chromatin structure by Cryo-FIB and Cryo-ET.Current opinion in structural biology · 2025
    Review
  19. Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Shiori IidaGenome Dynamics Laboratory, National Institute of Genetics, Research Organization of Information and Systems (ROIS), Mishima, Japan.ORCID 0000-0002-1115-4705
Soya ShinkaiLaboratory for Developmental Dynamics, RIKEN Center for Biosystems Dynamics Research, Kobe, Japan.ORCID 0000-0001-6852-2751
Yuji ItohGenome Dynamics Laboratory, National Institute of Genetics, Research Organization of Information and Systems (ROIS), Mishima, Japan.ORCID 0000-0002-6699-8665
Sachiko TamuraGenome Dynamics Laboratory, National Institute of Genetics, Research Organization of Information and Systems (ROIS), Mishima, Japan.
Masato T KanemakiDepartment of Genetics, School of Life Science, SOKENDAI, Mishima, Japan.ORCID 0000-0002-7657-1649
Shuichi OnamiLaboratory for Developmental Dynamics, RIKEN Center for Biosystems Dynamics Research, Kobe, Japan.ORCID 0000-0002-8255-1724
Kazuhiro MaeshimaGenome Dynamics Laboratory, National Institute of Genetics, Research Organization of Information and Systems (ROIS), Mishima, Japan.ORCID 0000-0003-3909-0341
National Institute of Genetics · JPRIKEN Center for Biosystems Dynamics Research · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dynamic chromatin behavior plays a critical role in various genome functions. However, it remains unclear how chromatin behavior changes during interphase, where the nucleus enlarges and genomic DNA doubles. While the previously reported chromatin movements varied during interphase when measured using a minute or longer time scale, we unveil that local chromatin motion captured by single-nucleosome imaging/tracking on a second time scale remained steady throughout G

Indexed as

ChromatinNucleosomesCell NucleusDNA ReplicationHumansInterphaseChromatinNucleosomes

Identifiers

PMID35658044
PMCPMC9166292
OpenAlexW4282036588

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.