Evidence map›Paper›PMID 35657777›Full record

ArticlePsychological science2022

Anxiety-Related Frontocortical Activity Is Associated With Dampened Stressor Reactivity in the Real World.

Juyoen Hur, Manuel Kuhn, Shannon E Grogans, Allegra S Anderson, Samiha Islam, Hyung Cho Kim, Rachael M Tillman, Andrew S Fox, Jason F Smith, Kathryn A DeYoung and 1 more

Open access · greenAbstract read
In one paragraph

Article in Psychological science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Structural Brain Correlates of Childhood Inhibited Temperament: An ENIGMA-Anxiety Mega-Analysis.Journal of the American Academy of Child and Adolescent Psychiatry · 2026
    Article
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  8. Fear, anxiety, and the extended amygdala-bioRxiv : the preprint server for biology · 2025
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  11. A Shared Threat-Anticipation Circuit Is Dynamically Engaged at Different Moments by Certain and Uncertain Threat.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  12. Article
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  15. Article
  16. Motivation and Pleasure Deficits Undermine the Benefits of Social Affiliation in Psychosis.Clinical psychological science : a journal of the Association for Psychological Science · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 2 countries.

Juyoen HurDepartment of Psychology, Yonsei University.
Manuel KuhnCenter for Depression, Anxiety and Stress Research, McLean Hospital, Harvard Medical School, Harvard University.
Shannon E GrogansDepartment of Psychology, University of Maryland.
Allegra S AndersonDepartment of Psychological Sciences, Vanderbilt University.
Samiha IslamDepartment of Psychology, University of Pennsylvania.ORCID 0000-0003-3238-7740
Hyung Cho KimDepartment of Psychology, University of Maryland.
Rachael M TillmanDepartment of Psychology, University of Maryland.
Andrew S FoxDepartment of Psychology, University of California, Davis.
Jason F SmithDepartment of Psychology, University of Maryland.
Kathryn A DeYoungDepartment of Psychology, University of Maryland.
Alexander J ShackmanDepartment of Psychology, University of Maryland.
University of Maryland, College Park · USHarvard University · USUniversity of California, Davis · USUniversity of Pennsylvania · USVanderbilt University · USYonsei University · KR

Funding

Using Multimodal Neuroimaging and Real-World Experience Sampling to Understand Negative Affect and Paranoid Ideation in PsychosisR01MH121409 · NIMH · UNIV OF MARYLAND, COLLEGE PARK · PI BLANCHARD, JACK J., SHACKMAN, ALEXANDER JOSEPH · 2020 to 2024
$3.7M
ORIGINS AND EMERGENCE OF MALADAPTIVE SOCIOEMOTIONAL BEHAVIOR DURING THE TRANSITION TO ADULTHOOD IN PRIMATESR01MH121735 · NIMH · UNIVERSITY OF CALIFORNIA AT DAVIS · PI FOX, ANDREW S · 2020 to 2025
$3.6M
Prospective Determination of Neurobehavioral Risk for the Development of Emotion DisordersR01MH107444 · NIMH · UNIV OF MARYLAND, COLLEGE PARK · PI SHACKMAN, ALEXANDER JOSEPH · 2016 to 2020
$3.4M
NIMH NIH HHS R01 MH107444NIMH NIH HHS R01 MH121409NIMH NIH HHS R01 MH121735
6 · The paper itself

Abstract

Negative affect is a fundamental dimension of human emotion. When extreme, it contributes to a variety of adverse outcomes, from physical and mental illness to divorce and premature death. Mechanistic work in animals and neuroimaging research in humans and monkeys have begun to reveal the broad contours of the neural circuits governing negative affect, but the relevance of these discoveries to everyday distress remains incompletely understood. Here, we used a combination of approaches-including neuroimaging assays of threat anticipation and emotional-face perception and more than 10,000 momentary assessments of emotional experience-to demonstrate that individuals who showed greater activation in a cingulo-opercular circuit during an anxiety-eliciting laboratory paradigm experienced lower levels of stressor-dependent distress in their daily lives (

Indexed as

AmygdalaAnxietyAnimalsEmotionsHumansMagnetic Resonance ImagingNeuroimaginganxietyemotionextended amygdalafearnegative affectnegative emotionalityneuroticism

Identifiers

PMID35657777
PMCPMC9343891
OpenAlexW4281965245

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.