Evidence map›Paper›PMID 35657705›Full record

ArticleJournal of bacteriology2022

The Phosphatase Bph and Peptidyl-Prolyl Isomerase PrsA Are Required for Gelatinase Expression and Activity in Enterococcus faecalis.

Julia L E Willett, Ethan B Robertson, Gary M Dunny

Open access · greenAbstract read
In one paragraph

Article in Journal of bacteriology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.1field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 21 citations in OpenAlex.

  1. Adaptation ofmSystems · 2026
    Article
  2. Article
  3. Membrane Vesicles ofMicroorganisms · 2025
    Article
  4. Article
  5. Insights into ecology, pathogenesis, and biofilm formation ofMicrobiology and molecular biology reviews : MMBR · 2025
    Review
  6. Article
  7. The Impact ofPathogens (Basel, Switzerland) · 2024
    Review
  8. Genotypic and phenotypic characterization ofbioRxiv : the preprint server for biology · 2024
    Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Julia L E WillettDepartment of Microbiology and Immunology, University of Minnesota Medical Schoolgrid.471402.4, Minneapolis, Minnesota, USA.
Ethan B RobertsonDepartment of Microbiology and Immunology, University of Minnesota Medical Schoolgrid.471402.4, Minneapolis, Minnesota, USA.
Gary M DunnyDepartment of Microbiology and Immunology, University of Minnesota Medical Schoolgrid.471402.4, Minneapolis, Minnesota, USA.
University of Minnesota Medical Center · US

Funding

University of Minnesota Clinical and Translational Science Institute (UMN CTSI)UL1TR002494 · NCATS · UNIVERSITY OF MINNESOTA · PI BLAZAR, BRUCE R, WEISDORF, DANIEL J · 2018 to 2022
$34.9M
Functional genomics analysis of colonization and persistence of Enterococcus faecalis in the gastrointestinal tract.R01AI122742 · NIAID · UNIVERSITY OF MINNESOTA · PI DUNNY, GARY M · 2016 to 2020
$2.2M
Enterococcal Sex pheromones: impact on antibiotic resistance transfer and ecology of the gastrointestinal tract.R35GM118079 · NIGMS · UNIVERSITY OF MINNESOTA · PI DUNNY, GARY M · 2016 to 2020
$2.1M
Functional genomics of hypothetical genes in Gram-positive bacteriaK99AI151080 · NIAID · UNIVERSITY OF MINNESOTA · PI WILLETT, JULIA · 2021 to 2022
$225k
HHS | National Institutes of Health (NIH) 1K99AI151080NCATS NIH HHS UL1 TR002494NIAID NIH HHS K99 AI151080NIAID NIH HHS R01 AI122742NIGMS NIH HHS R35 GM118079
6 · The paper itself

Abstract

Enterococcus faecalis is a common commensal bacterium in the gastrointestinal tract as well as a frequent nosocomial pathogen. The secreted metalloprotease gelatinase (GelE) is an important E. faecalis virulence factor that contributes to numerous cellular activities, such as autolysis, biofilm formation, and biofilm-associated antibiotic resistance. Expression of

Indexed as

Enterococcus faecalisGelatinasesBacterial ProteinsBiofilmsPeptidylprolyl IsomerasePhosphoric Monoester HydrolasesVirulence FactorsBacterial ProteinsGelatinasesPeptidylprolyl IsomerasePhosphoric Monoester HydrolasesVirulence FactorsbiofilmsEnterococcusgelatinasequorum sensing

Identifiers

PMID35657705
PMCPMC9295590
OpenAlexW4281614008

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.