Evidence map›Paper›PMID 35657632›Full record

ArticleArthritis care & research2023

Cost-Effectiveness of Surgical Weight-Loss Interventions for Patients With Knee Osteoarthritis and Class III Obesity.

Aleksandra M Kostic, Valia P Leifer, Yusi Gong, Malcolm K Robinson, Jamie E Collins, Tuhina Neogi, Stephen P Messier, David J Hunter, Faith Selzer, Lisa G Suter and 2 more

Open access · greenAbstract read
In one paragraph

Article in Arthritis care & research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 2 countries.

Aleksandra M KosticBrigham and Women's Hospital, Boston, Massachusetts.
Valia P LeiferBrigham and Women's Hospital, Boston, Massachusetts.
Yusi GongBrigham and Women's Hospital, Boston, Massachusetts, and Carle Illinois College of Medicine, Champaign.ORCID 0000-0003-0230-5863
Malcolm K RobinsonBrigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.
Jamie E CollinsBrigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.ORCID 0000-0001-8413-007X
Tuhina NeogiBoston University of School of Medicine, Boston, Massachusetts.ORCID 0000-0002-9515-1711
Stephen P MessierWake Forest University, Salem, North Carolina.ORCID 0000-0002-7033-8459
David J HunterRoyal North Shore Hospital, Kolling Institute, and University of Sydney, Sydney, New South Wales, Australia.ORCID 0000-0003-3197-752X
Faith SelzerBrigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.
Lisa G SuterYale School of Medicine and Yale-New Haven Health System, New Haven, and Veterans Affairs Medical Center, West Haven, Connecticut.
Jeffrey N KatzBrigham and Women's Hospital, Harvard Medical School, and Harvard T. H. Chan School of Public Health, Boston, Massachusetts.ORCID 0000-0003-2104-4670
Elena LosinaBrigham and Women's Hospital, Boston University School of Public Health, and Harvard Medical School, Boston, Massachusetts.ORCID 0000-0002-3424-0892
Brigham and Women's Hospital · USBoston University · USThe University of Sydney · AUWake Forest University · USYale New Haven Health System · US

Funding

VERITY: Value and Evidence in Rheumatology using bioInformaTics, and advanced analYticsP30AR072577 · NIAMS · BRIGHAM AND WOMEN'S HOSPITAL · PI Katherine Phoenix Liao · 2017 to 2026
$9.8M
Research and Evaluation Support Core Unit (RESCU Core)P30AR072571 · NIAMS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI Michael Paul Lavalley · 2019 to 2026
$6.9M
Optimizing the value of pain management in knee OA patients with comorbiditiesR01AR074290 · NIAMS · BRIGHAM AND WOMEN'S HOSPITAL · PI Elena Losina · 2018 to 2026
$5.9M
The Role of Urate in Knee Osteoarthritis-Related Inflammation, Pathology and PainK24AR070892 · NIAMS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI TUHINA NEOGI · 2017 to 2026
$1.1M
NIAMS NIH HHS K24 AR070892NIAMS NIH HHS P30 AR072571NIAMS NIH HHS P30 AR072577NIAMS NIH HHS R01 AR074290
6 · The paper itself

Abstract

objectiveClass III obesity (body mass index [BMI] ≥40 kg/m

methodsWe used the Osteoarthritis Policy model to assess long-term clinical benefits, costs, and cost-effectiveness of RYGB and LSG. We derived model inputs for efficacy, costs, and complications associated with these treatments from published data. Primary outcomes included quality-adjusted life-years (QALYs), lifetime costs, and incremental cost-effectiveness ratios (ICERs), all discounted at 3%/year. This analysis was conducted from a health care sector perspective. We performed sensitivity analyses to evaluate uncertainty in input parameters.

resultsThe usual care + RYGB strategy increased the quality-adjusted life expectancy by 1.35 years and lifetime costs by $7,209, compared to usual care alone (ICER = $5,300/QALY). The usual care + LSG strategy yielded less benefit than usual care + RYGB and was dominated. Relative to usual care alone, both usual care + RYGB and usual care + LSG reduced opioid use from 13% to 4%, and increased TKR usage from 30% to 50% and 41%, respectively. For cohorts with BMI between 38 and 41 kg/m

conclusionRYGB offers good value among knee OA patients with BMI ≥40 kg/m

Indexed as

Gastric BypassLaparoscopyObesity, MorbidOsteoarthritis, KneeCost-Benefit AnalysisGastrectomyHumansObesityWeight Loss

Identifiers

PMID35657632
PMCPMC9827536
OpenAlexW4281764268

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.