Evidence map›Paper›PMID 35657419›Full record

ArticleBrain structure & function2022

Modelling the laminar connectome of the human brain.

Ittai Shamir, Omri Tomer, Ronnie Krupnik, Yaniv Assaf

Abstract read
PubMed Publisher
In one paragraph

Article in Brain structure & function, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
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  4. Article
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  7. Article
  8. Expanding connectomics to the laminar level: A perspective.Network neuroscience (Cambridge, Mass.) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Ittai ShamirDepartment of Neurobiology, Faculty of Life Sciences, Tel Aviv University, Tel Aviv, Israel. ittaisha@mail.tau.ac.il.ORCID http://orcid.org/0000-0003-4028-5154
Omri TomerSagol School of Neuroscience, Tel Aviv University, Tel Aviv, Israel.
Ronnie KrupnikSagol School of Neuroscience, Tel Aviv University, Tel Aviv, Israel.
Yaniv AssafDepartment of Neurobiology, Faculty of Life Sciences, Tel Aviv University, Tel Aviv, Israel.
Tel Aviv University · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The human connectome is the complete structural description of the network of connections and elements that form the 'wiring diagram' of the brain. Due to the current scarcity of information regarding laminar end points of white matter tracts inside cortical grey matter, tractography remains focused on cortical partitioning into regions, while ignoring radial partitioning into laminar components. To overcome this biased representation of the cortex as a single homogenous unit, we use a recent data-derived model of cortical laminar connectivity, which has been further explored and corroborated in the macaque brain by comparison to published studies. The model integrates multimodal MRI imaging datasets of both white matter connectivity and grey matter laminar composition into a laminar-level connectome. In this study, we model the laminar connectome of healthy human brains (N = 30) and explore them via a set of complex network measures. Our analysis demonstrates a subdivision of network hubs that appear in the standard connectome into each individual component of the laminar connectome, giving a fresh look into the role of laminar components in cortical connectivity and offering new prospects in the fields of both structural and functional connectivity.

Indexed as

ConnectomeWhite MatterBrainGray MatterHumansMagnetic Resonance ImagingAnatomical mappingBrain network analysisComputational modelsConnectomicsCortical layersNeuronal structures

Identifiers

PMID35657419
OpenAlexW4281665419

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.