Evidence map›Paper›PMID 35656973›Full record

Trial reportJournal of the American Heart Association2022

Intervention Adherence in REHAB-HF: Predictors and Relationship With Physical Function, Quality of Life, and Clinical Events.

M Benjamin Nelson, Olivia N Gilbert, Pamela W Duncan, Dalane W Kitzman, Gordon R Reeves, David J Whellan, Robert J Mentz, Haiying Chen, Leigh Ann Hewston, Karen M Taylor and 1 more

Open access · goldAbstract readClinical Trial
In one paragraph

Trial report in Journal of the American Heart Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 19 citations in OpenAlex.

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  16. Demographic, Clinical, and Psychosocial Predictors of Exercise Adherence: The STRRIDE Trials.Translational journal of the American College of Sports Medicine · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

M Benjamin NelsonDepartment of Internal Medicine Section on Cardiovascular Medicine Wake Forest School of Medicine Winston-Salem NC.
Olivia N GilbertDepartment of Internal Medicine Section on Cardiovascular Medicine Wake Forest School of Medicine Winston-Salem NC.ORCID 0000-0003-3151-6029
Pamela W DuncanDepartment of Neurology Wake Forest School of Medicine Winston-Salem NC.ORCID 0000-0002-4838-3253
Dalane W KitzmanDepartment of Internal Medicine Section on Cardiovascular Medicine Wake Forest School of Medicine Winston-Salem NC.
Gordon R ReevesNovant Health Heart and Vascular Institute Charlotte NC.
David J WhellanDepartment of Medicine Sidney Kimmel Medical College at Thomas Jefferson University Philadelphia PA.
Robert J MentzDepartment of Medicine Division of Cardiology Duke University School of Medicine Durham NC.ORCID 0000-0002-3222-1719
Haiying ChenDepartment of Biostatistics and Data Science Wake Forest School of Medicine Winston-Salem NC.
Leigh Ann HewstonDepartment of Physical Therapy Jefferson College of Rehabilitation Sciences at Thomas Jefferson University Philadelphia PA.
Karen M TaylorDepartment of Physical and Occupational Therapy Atrium Health Wake Forest Baptist Winston-Salem NC.
Amy M PastvaDepartment of Orthopedic Surgery Doctor of Physical Therapy Division Duke University School of Medicine Durham NC.ORCID 0000-0002-0891-745X
Wake Forest University · USDuke University · USThomas Jefferson University · USAtrium Health Wake Forest Baptist · USNovant Health · US

Funding

Wake Forest Claude D. Pepper OAIC - RenewalP30AG021332 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Denise Kathryn Houston · 2002 to 2026
$36.4M
Wake Forest Clinical and Translational Science AwardUL1TR001420 · NCATS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI ARD, JAMY D, FOLEY, KRISTIE L · 2015 to 2023
$32.3M
Resource Core 3 - Metabolomics CoreP30AG028716 · NIA · DUKE UNIVERSITY · PI Sarah B. Peskoe · 2006 to 2026
$24.6M
REHAB-HF: A Trial of Rehabilitation Therapy in Older Acute Heart Failure PatientsR01AG045551 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI KITZMAN, DALANE W · 2014 to 2018
$6.8M
Pepper OAIC Coordinating CenterU24AG059624 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI DALANE W KITZMAN · 2018 to 2026
$6.0M
Exercise Intolerance in Older HFPEF PatientsR01AG018915 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI KITZMAN, DALANE W · 2001 to 2019
$5.2M
NCATS NIH HHS UL1 TR001420NIA NIH HHS P30 AG021332NIA NIH HHS P30 AG028716NIA NIH HHS R01 AG018915NIA NIH HHS R01 AG045551NIA NIH HHS U24 AG059624
6 · The paper itself

Abstract

Background The REHAB-HF (Rehabilitation Therapy in Older Acute Heart Failure Patients) trial showed that a novel, early, transitional, tailored, progressive, multidomain physical rehabilitation intervention improved physical function and quality of life in older, frail patients hospitalized for acute decompensated heart failure. This analysis examined the relationship between intervention adherence and outcomes. Methods and Results Adherence was defined as percent of sessions attended and percent of sessions attended adjusted for missed sessions for medical reasons. Baseline characteristics were examined to identify predictors of session attendance. Associations of session attendance with change in physical function (Short Physical Performance Battery [primary outcome], 6-minute walk distance, quality of life [Kansas City Cardiomyopathy Questionnaire], depression, and clinical events [landmarked postintervention]) were examined in multivariate analyses. Adherence was 67%±34%, and adherence adjusted for missed sessions for medical reasons was 78%±34%. Independent predictors of higher session attendance were the following: nonsmoking, absence of myocardial infarction history and depression, and higher baseline Short Physical Performance Battery. After adjustment for predictors, adherence was significantly associated with larger increases in Short Physical Performance Battery (parameter estimate: β=0.06[0.03-0.10],

Indexed as

CardiomyopathiesHeart FailureAgedExercise TherapyHospitalizationHumansQuality of Lifeadherenceheart failurephysical functionquality of liferehabilitation

Identifiers

PMID35656973
PMCPMC9238741
OpenAlexW4281953282

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.