Evidence map›Paper›PMID 35656707›Full record

ArticlePhysiological reports2022

Feasibility study of defecation studied with a wireless Fecobionics probe in normal subjects.

Hans Gregersen, Yanmin Wang, Fred Field, Mengjun Wang, Kar Man Lo, Xiaomei Guo, William Combs, Ghassan S Kassab

Open access · goldAbstract read
In one paragraph

Article in Physiological reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Consistency of Feces Affects Defecatory Function.Journal of neurogastroenterology and motility · 2024
    Article
  5. Fecobionics in proctology: review and perspectives.Surgery open digestive advance · 2023
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Hans GregersenCalifornia Medical Innovations Institute, San Diego, California, USA.ORCID 0000-0002-5792-2845
Yanmin WangCalifornia Medical Innovations Institute, San Diego, California, USA.
Fred Field3DT, San Diego, California, USA.
Mengjun Wang3DT, San Diego, California, USA.
Kar Man LoCalifornia Medical Innovations Institute, San Diego, California, USA.
Xiaomei GuoCalifornia Medical Innovations Institute, San Diego, California, USA.
William Combs3DT, San Diego, California, USA.
Ghassan S KassabCalifornia Medical Innovations Institute, San Diego, California, USA.
California Medical Innovations Institute · USUniversity of San Diego · US

Funding

Neurophysiological mechanism in sacral neuromodulation in patients suffering from fecal incontinenceOT2OD028203 · OD · CALIFORNIA MEDICAL INNOVATIONS INSTITUTE · PI GREGERSEN, HANS · 2019 to 2021
$3.1M
NIH HHS OT2 OD028203NIH HHS OT2ODO28203
6 · The paper itself

Abstract

Several technologies have been developed for assessing anorectal function including the act of defecation. We used a new prototype of the Fecobionics technology, a multi-sensor simulated feces, to visualize defecatory patterns and introduced new metrics for anorectal physiology assessment in normal subjects. Fourteen subjects with normal fecal incontinence and constipation questionnaire scores were studied. The 10-cm-long Fecobionics device provided measurements of axial pressures, orientation, bending, and shape. The Fecobionics bag was distended to the urge-to-defecate level inside rectum where after the subjects were asked to evacuate. Physiological evacuation parameters were assessed. Special attention was paid to the Fecobionics rectoanal pressure gradient (F-RAPG) during evacuation. Anorectal manometry (ARM) and balloon expulsion test (BET) were done as references. The user interface displayed the fine coordination between pressures, orientation, bending angle, and shape. The pressures showed that Fecobionics was expelled in 11.5 s (quartiles 7.5 and 18.8s), which was shorter than the subjectively reported expulsion time of the BET balloon. Six subjects did not expel the BET balloon within 2 min. The F-RAPG was 101 (79-131) cmH

Indexed as

Anal CanalDefecationFeasibility StudiesHumansManometryRectumanal sphincter relaxationanorectal physiologybionicsdefecationfecobionicsrectoanal pressure gradient RAPG

Identifiers

PMID35656707
PMCPMC9163794
OpenAlexW4281711401

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.