Evidence map›Paper›PMID 35656593›Full record

ArticleJournal of medical virology2022

Analytical sensitivity of the Rapid Antigen Test kits for detection of SARS-CoV-2 Omicron variant BA.2 sublineage.

Gannon C K Mak, Stephen S Y Lau, Kitty K Y Wong, Chi-Shan Lau, Ken H L Ng, Edman T K Lam, Rickjason C W Chan

Abstract read
In one paragraph

Article in Journal of medical virology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Gannon C K MakMicrobiology Division, Public Health Laboratory Services Branch, Department of Health, Centre for Health Protection, Hong Kong Special Administrative Region, Kowloon, Hong Kong.ORCID 0000-0003-0893-533X
Stephen S Y LauMicrobiology Division, Public Health Laboratory Services Branch, Department of Health, Centre for Health Protection, Hong Kong Special Administrative Region, Kowloon, Hong Kong.
Kitty K Y WongMicrobiology Division, Public Health Laboratory Services Branch, Department of Health, Centre for Health Protection, Hong Kong Special Administrative Region, Kowloon, Hong Kong.
Chi-Shan LauMicrobiology Division, Public Health Laboratory Services Branch, Department of Health, Centre for Health Protection, Hong Kong Special Administrative Region, Kowloon, Hong Kong.
Ken H L NgMicrobiology Division, Public Health Laboratory Services Branch, Department of Health, Centre for Health Protection, Hong Kong Special Administrative Region, Kowloon, Hong Kong.
Edman T K LamMicrobiology Division, Public Health Laboratory Services Branch, Department of Health, Centre for Health Protection, Hong Kong Special Administrative Region, Kowloon, Hong Kong.
Rickjason C W ChanMicrobiology Division, Public Health Laboratory Services Branch, Department of Health, Centre for Health Protection, Hong Kong Special Administrative Region, Kowloon, Hong Kong.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) Omicron was classified as a variant of concern in November 2021. The sublineage BA.2 spreads rapidly worldwide. Currently, there is a lack of data for the parallel comparison of Rapid Antigen Test (RAT) Kits to detect SARS-CoV-2 Omicron BA.2. We evaluated the analytical sensitivity of 12 RAT kits to detect Omicron BA.2 in the present study. Analytical sensitivity was determined by means of the limit of detection (LOD). We prepared a dilution set using a respiratory specimen collected from a COVID-19 patient infected by Omicron BA.2. The reverse transcription-polymerase chain reaction was used as a reference method. The LOD results showed that all 12 RAT kits had comparable analytical sensitivity to detect Omicron BA.2. The RAT kits selected in the current study may be used for the first-line screening of the rapid spreading Omicron BA.2.

Indexed as

COVID-19SARS-CoV-2HumansImmunologic TestsRNA, ViralRNA, ViralB.1.1.529BA.2COVID-19OmicronRapid Antigen TestSARS-CoV-2

Identifiers

PMID35656593
PMCPMC9347738

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.