ArticleColorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland2022
Long term oncological outcomes for laparoscopic versus open surgery for rectal cancer - A population-based nationwide noninferiority study.
Article in Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Impact of laparoscopic versus open surgery on humoral immunity in patients with colorectal cancer: a systematic review and meta-analysis.Surgical endoscopy · 2024Pooled it
- Impact of acute sleep deprivation on laparoscopic performance: a prospective, randomized crossover trial.Surgical endoscopy · 2026Trial
- Developing a multivariable prediction model of global health-related quality of life in patients treated for rectal cancer: a prospective study in five countries.International journal of colorectal disease · 2024Trial
- Short-term outcomes in robotic-assisted versus conventional laparoscopic surgery for rectal cancer: population-based study.BJS open · 2026Article
- Missingness in Eligibility Criteria for Target Trial Emulation in EHR With Survival Outcomes.Statistics in medicine · 2026Article
- Review
- Does socioeconomic status influence the choice of surgical technique in abdominal rectal cancer surgery?Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2025Article
- Long-term survival outcomes of laparoscopic surgery in patients with colorectal cancer: A propensity score matching retrospective cohort study.Chinese journal of cancer research = Chung-kuo yen cheng yen chiu · 2024Article
- Low ligation of the inferior mesenteric artery in robotic mid-low rectal cancer surgery: a comparative study from a single-center.Journal of robotic surgery · 2024Article
- Robotic-assisted vs. open ureteral reimplantation: a multicentre comparison.World journal of urology · 2024Article
- Short-term results in a population based study indicate advantage for minimally invasive rectal cancer surgery versus open.BMC surgery · 2024Article
- Robotic Total Mesorectal Excision for Low Rectal Cancer: A Narrative Review and Description of the Technique.Journal of clinical medicine · 2023Article
- Influence of Laparoscopic Surgery on Cellular Immunity in Colorectal Cancer: A Systematic Review and Meta-Analysis.Cancers · 2023Review
- Long term oncological outcomes for laparoscopic versus open surgery for rectal cancer - A population-based nationwide noninferiority study.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2022Article
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5 authors.
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Abstract
aimThe aim of this work was to compare the 5-year overall survival in a national cohort of patients undergoing curative abdominal resection for rectal cancer by laparoscopic (LAP) or open (OPEN) surgery.
methodAll patients diagnosed with clinical Stage I-III rectal cancer and who underwent LAP or OPEN abdominal curative surgery in Sweden between 2010 and 2016 were retrieved from the Swedish Colorectal Cancer Registry. A noninferiority study design was employed with a statistical power of 90%, a one-side type I error of 2.5% and a noninferiority margin of 2%. The analyses were performed as intention-to-treat and the relationship between surgical technique and overall mortality within 5 years was analysed. Multilevel regression models with the patients matched by propensity scores adjusted for patient- and tumour-related variables were used.
resultsA total of 8410 Stage I-III cancer patients were included. This group underwent 2094 LAP (24.9%) and 6316 OPEN (75.1%) procedures and were followed until 31 December 2020. Multivariable Cox regression demonstrated that 5-year overall survival was higher in the LAP group [hazard ratio (HR) 0.877; 95% CI 0.775-0.993]. [Correction added on 21 November 2022, after first online publication: In the preceding sentence, the CI value for LAP group has been corrected from "0.877" to "0.775" in this version.] The outcome was similar when multiple imputation and propensity score matching were employed. When cT4 patients were excluded there was no difference (HR 0.885; 95% CI 0.790-1.033). At 5-years' follow-up local recurrence was not different, at 2.9% for the LAP group and 3.6% for the OPEN group (p = 0.075), while metastatic disease was more frequent in the OPEN group (19.6% compared with 15.6% for LAP; p < 0.001).
conclusionThis study demonstrated that the LAP technique was not inferior to OPEN surgery with regard to overall 5-year survival. These results support the use of laparoscopic surgery.
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