Evidence map›Paper›PMID 35656455›Full record

ArticleInternational journal of tryptophan research : IJTR2022

Tryptophan and Biogenic Amines in the Differentiation and Quality of Honey.

Cristine Vanz Borges, Aline Nunes, Vladimir Eliodoro Costa, Ricardo de Oliveira Orsi, Leticia Silva Pereira Basilio, Gean Charles Monteiro, Marcelo Maraschin, Giuseppina Pace Pereira Lima

Abstract read
In one paragraph

Article in International journal of tryptophan research : IJTR, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Review
  6. Evolutionary formation of melatonin and vitamin D in early life forms: insects take centre stage.Biological reviews of the Cambridge Philosophical Society · 2024
    Review
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Cristine Vanz BorgesHealth Sciences, Universidade Alto Vale do Rio do Peixe (UNIARP), Caçador, Santa Catarina, Brazil.
Aline NunesPlant Morphogenesis and Biochemistry Laboratory, Federal University of Santa Catarina, Florianopolis, Santa Catarina, Brazil.
Vladimir Eliodoro CostaStable Isotope Center, Institute of Biosciences, São Paulo State University, Botucatu, São Paulo, Brazil.ORCID https://orcid.org/0000-0003-3889-7514
Ricardo de Oliveira OrsiCenter of Education, Science and Technology in Rational Beekeeping (NECTAR), College of Veterinary Medicine and Animal Sciences, São Paulo State University, Botucatu, São Paulo, Brazil.
Leticia Silva Pereira BasilioDepartment of Chemical and Biological Sciences, Institute of Biosciences, São Paulo State University, Botucatu, São Paulo, Brazil.
Gean Charles MonteiroDepartment of Chemical and Biological Sciences, Institute of Biosciences, São Paulo State University, Botucatu, São Paulo, Brazil.ORCID https://orcid.org/0000-0001-6072-8018
Marcelo MaraschinPlant Morphogenesis and Biochemistry Laboratory, Federal University of Santa Catarina, Florianopolis, Santa Catarina, Brazil.
Giuseppina Pace Pereira LimaDepartment of Chemical and Biological Sciences, Institute of Biosciences, São Paulo State University, Botucatu, São Paulo, Brazil.ORCID https://orcid.org/0000-0002-1792-2605

Funding

South Carolina Clinical & Translational Research Institute (SCTR)KL2TR001452 · NCATS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI MCRAE-CLARK, AIMEE L · 2015 to 2024
$5.9M
NCATS NIH HHS KL2 TR001452
6 · The paper itself

Abstract

Honey is a natural product with beneficial properties to health and has different characteristics depending on the region of production and collection, flowering, and climate. The presence of precursor amino acids of- and biogenic amines can be important in metabolomic studies of differentiation and quality of honey. We analyzed 65 honeys from 11 distinct regions of the State of Santa Catarina (Brazil) as to the profile of amino acids and biogenic amines by HPLC. The highest L-tryptophan (Trp), 5-hydroxytryptophan (5-OH-Trp), and tryptamine (Tryp) levels were detected in Cfb climate and harvested in 2019. Although we have found high content of serotonin, dopamine, and L-dopa in Cfb climate, the highest values occurred in honey produced during the summer 2018 and at altitudes above 900 m. Results indicate that the amino acids and biogenic amine levels in honeys are good indicators of origin. These data warrant further investigation on the honey as source of amino acids precursor of serotonin, melatonin, and dopamine, what can guide the choice of food as source of neurotransmitters.

Indexed as

dopamineL-dopaL-tryptophanmelatoninserotonin

Identifiers

PMID35656455
PMCPMC9152190

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.