ReviewFrontiers in psychiatry2022
Targeting the Salience Network: A Mini-Review on a Novel Neuromodulation Approach for Treating Alcohol Use Disorder.
Review in Frontiers in psychiatry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06949423 (Accessing the Impact of Deep TMS Neuromodulation on Neural Circuits Associated With Alcohol Use Disorder), which is not on this map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Accessing the Impact of Deep TMS Neuromodulation on Neural Circuits Associated With Alcohol Use Disorder
Who cites it
24 citing papers in PubMed, 31 citations in OpenAlex.
- Intermittent theta burst to the left dorsolateral prefrontal cortex promoted decreased alcohol consumption and improved outcomes in those with alcohol use disorder: A randomized, double-blind, placebo-controlled clinical trial.Drug and alcohol dependence · 2025Trial
- Drawbacks to Strengthening Neural Salience Encoding: A Link Between Cortisol and Risky Drinking.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Trial
- Corticotropin-Releasing Factor receptor 1 (CRF1) antagonism in patients with alcohol use disorder and high anxiety levels: effect on neural response during Trier Social Stress Test video feedback.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2023Trial
- Whole-Brain Structural Connectivity Alterations in Chronic Subjective Tinnitus: An Exploratory Diffusion Tensor Imaging Study.Brain sciences · 2026Article
- Network localization of gray matter alterations in chronic smokers using the normative functional connectome.Frontiers in public health · 2026Article
- Crosstalk between alcohol use disorder and obesity: two sides of the same coin?Molecular psychiatry · 2025Review
- Neurobiological Mechanisms of Action of Transcranial Direct Current Stimulation (tDCS) in the Treatment of Substance Use Disorders (SUDs)-A Review.Journal of clinical medicine · 2025Review
- Action-mode subnetworks for decision-making, action control, and feedback.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- A Customized Neural Transcranial Magnetic Stimulation Target for Functional Disability Among Veterans With Co-Occurring Alcohol Use Disorder and Mild Traumatic Brain Injury: Protocol for a Pilot Randomized Controlled Trial.JMIR research protocols · 2025Article
- A Meta-Analysis of Task-Based fMRI Studies on Alcohol Use Disorder.Brain sciences · 2025Review
- Functional brain connectivity of the salience network in alcohol use and anxiety disorders.Journal of affective disorders · 2025Article
- Efficacy of Transcranial Direct Current Stimulation (tDCS) on Neuropsychiatric Symptoms in Substance Use Disorder (SUD)-A Review and Insights into Possible Mechanisms of Action.Journal of clinical medicine · 2025Review
- Neuroscience-informed psychoeducation for addiction: a conceptual and feasibility study.Frontiers in psychiatry · 2025Article
- Neural correlates of executive dysfunction in alcohol use disorder: preliminary evidence fromFrontiers in psychology · 2025Article
- Effects of intermittent theta burst to the left dorsolateral prefrontal cortex on brain volumes and neurometabolites in people with alcohol use disorder: a preliminary investigation.Frontiers in human neuroscience · 2025Article
- Alterations in functional connectivity in the salience network shared by depressive symptoms and smartphone overuse.Scientific reports · 2024Article
- Regional cortical brain volumes at treatment entry relates to post treatment WHO risk drinking levels in those with alcohol use disorder.Drug and alcohol dependence · 2024Article
- Early life stress and body-mass-index modulate brain connectivity in alcohol use disorder.Translational psychiatry · 2024Article
- Psychological dimensions in alcohol use disorder: comparing active drinkers and abstinent patients.Frontiers in psychiatry · 2024Article
- The Brain Salience Network at the Intersection of Pain and Substance use Disorders: Insights from Functional Neuroimaging Research.Current addiction reports · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 5 institutions in 1 country.
Funding
Abstract
Alcohol use disorder (AUD) continues to be challenging to treat despite the best available interventions, with two-thirds of individuals going on to relapse by 1 year after treatment. Recent advances in the brain-based conceptual framework of addiction have allowed the field to pivot into a neuromodulation approach to intervention for these devastative disorders. Small trials of repetitive transcranial magnetic stimulation (rTMS) have used protocols developed for other psychiatric conditions and applied them to those with addiction with modest efficacy. Recent evidence suggests that a TMS approach focused on modulating the salience network (SN), a circuit at the crossroads of large-scale networks associated with AUD, may be a fruitful therapeutic strategy. The anterior insula or dorsal anterior cingulate cortex may be particularly effective stimulation sites given emerging evidence of their roles in processes associated with relapse.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.