Evidence map›Paper›PMID 35656342›Full record

ArticleStatistical analysis and data mining2022

Bag of little bootstraps for massive and distributed longitudinal data.

Xinkai Zhou, Jin J Zhou, Hua Zhou

Abstract read
In one paragraph

Article in Statistical analysis and data mining, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Xinkai ZhouDepartment of Biostatistics, University of California, Los Angeles, California, USA.
Jin J ZhouDepartment of Medicine, University of California, Los Angeles, California, USA.
Hua ZhouDepartment of Biostatistics, University of California, Los Angeles, California, USA.ORCID 0000-0003-1320-7118

Funding

Genomics, GPUs, and Next Generation Computational StatisticsR01HG006139 · NHGRI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI SOBEL, ERIC · 2011 to 2023
$5.1M
Modeling, Inference, and Optimization for Genomic and Biomedical Big DataR35GM141798 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI LANGE, KENNETH L · 2021 to 2025
$2.7M
Develop T2D Patient-Centered Treatment Suggestion Rule using EMR dataK01DK106116 · NIDDK · UNIVERSITY OF ARIZONA · PI ZHOU, JIN · 2016 to 2019
$524k
A Role for Glycemic Variation in Optimizing Management of Diabetes and Vascular ComplicationsR21HL150374 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI REAVEN, PETER D, ZHOU, JIN · 2020 to 2021
$250k
NHGRI NIH HHS R01 HG006139NHLBI NIH HHS R21 HL150374NIDDK NIH HHS K01 DK106116NIGMS NIH HHS R35 GM141798
6 · The paper itself

Abstract

Linear mixed models are widely used for analyzing longitudinal datasets, and the inference for variance component parameters relies on the bootstrap method. However, health systems and technology companies routinely generate massive longitudinal datasets that make the traditional bootstrap method infeasible. To solve this problem, we extend the highly scalable bag of little bootstraps method for independent data to longitudinal data and develop a highly efficient Julia package MixedModelsBLB.jl. Simulation experiments and real data analysis demonstrate the favorable statistical performance and computational advantages of our method compared to the traditional bootstrap method. For the statistical inference of variance components, it achieves 200 times speedup on the scale of 1 million subjects (20 million total observations), and is the only currently available tool that can handle more than 10 million subjects (200 million total observations) using desktop computers.

Indexed as

bags of little bootstrapsbig dataEMRlinear mixed modelslongitudinal dataparallel and distributed computing

Identifiers

PMID35656342
PMCPMC9159544

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.