Evidence map›Paper›PMID 35656148›Full record

ArticleJournal of lipid and atherosclerosis2022

Prognostic Value of Baseline Neutrophil-to-Lymphocyte Ratio Combined With Anemia in Patients With ST-Segment Elevation Myocardial Infarction: A Nationwide Prospective Cohort Study.

Kyung Hoon Cho, Min-Ho Shin, Min Chul Kim, Doo Sun Sim, Young Joon Hong, Ju Han Kim, Youngkeun Ahn, Shung Chull Chae, In Whan Seong, Jong-Seon Park and 5 more

Open access · diamondAbstract read
In one paragraph

Article in Journal of lipid and atherosclerosis, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Are OnlyJournal of lipid and atherosclerosis · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 8 institutions in 1 country.

Kyung Hoon ChoDepartment of Cardiology, Chonnam National University Hospital, Gwangju, Korea.ORCID https://orcid.org/0000-0002-0377-6352
Min-Ho ShinDepartment of Preventive Medicine, Chonnam National University Medical School, Hwasun, Korea.ORCID https://orcid.org/0000-0002-2217-5624
Min Chul KimDepartment of Cardiology, Chonnam National University Hospital, Gwangju, Korea.ORCID https://orcid.org/0000-0001-6026-1702
Doo Sun SimDepartment of Cardiology, Chonnam National University Hospital, Gwangju, Korea.ORCID https://orcid.org/0000-0003-4162-7902
Young Joon HongDepartment of Cardiology, Chonnam National University Hospital, Gwangju, Korea.ORCID https://orcid.org/0000-0003-0192-8161
Ju Han KimDepartment of Cardiology, Chonnam National University Hospital, Gwangju, Korea.ORCID https://orcid.org/0000-0002-3186-0770
Youngkeun AhnDepartment of Cardiology, Chonnam National University Hospital, Gwangju, Korea.ORCID https://orcid.org/0000-0003-2022-9366
Shung Chull ChaeDepartment of Cardiology, Kyungpook National University Hospital, Daegu, Korea.ORCID https://orcid.org/0000-0002-9871-6976
In Whan SeongDepartment of Cardiology, Chungnam National University Hospital, Daejeon, Korea.ORCID https://orcid.org/0000-0003-4628-0258
Jong-Seon ParkDepartment of Cardiology, Yeungnam University Hospital, Daegu, Korea.ORCID https://orcid.org/0000-0001-5242-2756
Chang-Hwan YoonDepartment of Cardiology, Seoul National University Bundang Hospital, Seongnam, Korea.ORCID https://orcid.org/0000-0001-6305-4442
Seung Ho HurDepartment of Cardiology, Keimyung University Dongsan Medical Center, Daegu, Korea.ORCID https://orcid.org/0000-0002-3895-1915
Sang Rok LeeDepartment of Cardiology, Jeonbuk National University Hospital, Jeonju, Korea.ORCID https://orcid.org/0000-0002-5845-2232
Myung Ho JeongDepartment of Cardiology, Chonnam National University Hospital, Gwangju, Korea.ORCID https://orcid.org/0000-0003-2424-810X
Korea Acute Myocardial Infarction Registry-National Institutes of Health (KAMIR-NIH) Investigators
Chonnam National University Hospital · KRChonnam National University Hwasun Hospital · KRChungnam National University Hospital · KRJeonbuk National University Hospital · KRKeimyung University Dongsan Medical Center · KRKyungpook National University Hospital · KRSeoul National University Bundang Hospital · KRYeungnam University Medical Center · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Data pertaining to the prognostic value of the combination of high neutrophil-to-lymphocyte ratio (NLR) and anemia on admission in patients with ST-segment elevation myocardial infarction (STEMI) are limited. The objective of this study was to investigate the clinical value of baseline NLR in combination with anemia in predicting clinical outcomes after STEMI. Methods: A total of 5,194 consecutive patients with STEMI within 12 hours of symptom onset from the Korea Acute Myocardial Infarction Registry-National Institute of Health database between 2011 and 2015 were categorized into 4 groups according to their NLR and hemoglobin levels: low NLR (<4) without anemia (n=2,722; reference group); high NLR (≥4) without anemia (n=1,527); low NLR with anemia (n=508); and high NLR with anemia (n=437). The co-primary outcomes were 180-day and 3-year all-cause mortality. Results: Mortality rates significantly increased at the 3-year follow-up across the groups (3.3% vs. 5.4% vs. 16.5% vs. 21.7% for 180-day mortality and 5.3% vs. 9.0% vs. 23.8% vs. 33.4% for 3-year mortality; all Conclusions: This nationwide prospective cohort study showed that the combination of high NLR (≥4) and anemia is a strong predictor of all-cause mortality after STEMI.

Indexed as

AnemiaLymphocytesNeutrophilsST elevation myocardial infarction

Identifiers

PMID35656148
PMCPMC9133781
OpenAlexW4282929804

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.