Evidence map›Paper›PMID 35656112›Full record

ArticleAging and disease2022

DR1 Activation Inhibits the Proliferation of Vascular Smooth Muscle Cells through Increasing Endogenous H

Yuxin Xi, Xin Wen, Yuanzhou Zhang, Lijie Jiao, Shuzhi Bai, Sa Shi, Guiquan Chang, Ren Wu, Fengqi Sun, Jinghui Hao and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Aging and disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Yuxin Xi1Department of Pathophysiology, Harbin Medical University, Harbin, Heilongjiang, China.
Xin Wen1Department of Pathophysiology, Harbin Medical University, Harbin, Heilongjiang, China.
Yuanzhou Zhang3State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Lijie Jiao2School of Medicine, Xiamen University, Xiamen, Fujian, China.
Shuzhi Bai1Department of Pathophysiology, Harbin Medical University, Harbin, Heilongjiang, China.
Sa Shi1Department of Pathophysiology, Harbin Medical University, Harbin, Heilongjiang, China.
Guiquan Chang1Department of Pathophysiology, Harbin Medical University, Harbin, Heilongjiang, China.
Ren Wu1Department of Pathophysiology, Harbin Medical University, Harbin, Heilongjiang, China.
Fengqi Sun1Department of Pathophysiology, Harbin Medical University, Harbin, Heilongjiang, China.
Jinghui Hao1Department of Pathophysiology, Harbin Medical University, Harbin, Heilongjiang, China.
Hongzhu Li1Department of Pathophysiology, Harbin Medical University, Harbin, Heilongjiang, China.
Harbin Medical University · CNXiamen University · CNShanghai Jiao Tong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tissue ischemia and hypoxia caused by the abnormal proliferation of smooth muscle cells (SMCs) in the diabetic state is an important pathological basis for diabetic microangiopathy. Studies in recent years have shown that the chronic complications of diabetes are related to the decrease of endogenous hydrogen sulfide (H

Indexed as

diabetesDopamine 1-like receptorsH2Svascular smooth muscle cells

Identifiers

PMID35656112
PMCPMC9116912
OpenAlexW4282917224

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.