Evidence map›Paper›PMID 35656057›Full record

ArticleIndian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine2022

Case of Suspected SARS-CoV-2 Vaccine-induced Immune Thrombotic Thrombocytopenia: Dilemma for Organ Donation.

Anand M Tiwari, Kapil G Zirpe, Sushma K Gurav, Lomesh B Bhirud, Rupali S Suryawanshi, Shilpa S Kulkarni

Open access · diamondAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Anand M TiwariNeuro Trauma Unit, Ruby Hall Clinic, Pune, Maharashtra, India.ORCID https://orcid.org/0000-0002-9791-8365
Kapil G ZirpeNeuro Trauma Unit, Grant Medical Foundation, Pune, Maharashtra, India.ORCID https://orcid.org/0000-0002-8140-727X
Sushma K GuravNeuro Trauma Unit, Grant Medical Foundation, Pune, Maharashtra, India.ORCID https://orcid.org/0000-0001-6875-2071
Lomesh B BhirudDepartment of Neurology, Grant Medical Foundation, Pune, Maharashtra, India.ORCID https://orcid.org/0000-0002-1094-2806
Rupali S SuryawanshiDepartment of Laboratory, Grant Medical Foundation, Pune, Maharashtra, India.ORCID https://orcid.org/0000-0001-7954-7225
Shilpa S KulkarniDepartment of Critical Care, Ruby Hall Clinic, Pune, Maharashtra, India.ORCID https://orcid.org/0000-0002-1159-2748
Grant Medical College and Sir Jamshedjee Jeejeebhoy Group of Hospitals · INGrant Medical Center · USRuby Hall Clinic · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Several vaccines were developed and rolled out at an unprecedented rate in response to the coronavirus disease-2019 (COVID-19) pandemic. Most vaccines approved globally by WHO for emergency use to combat the pandemic were deemed remarkably effective and safe. Despite the safety, rare incidences of vaccine-induced thrombosis and thrombocytopenia (VITT), sometimes known as vaccine-induced prothrombotic thrombocytopenia (VIPIT), have been reported. We report a case of young female with prothrombotic conditions and suspected VITT who developed catastrophic cerebral venous sinus thrombosis (CVST) and progressed to brain death. We highlight hurdles of organ retrieval from a brain-dead patient with suspected SARS-CoV-2 vaccine-induced immune thrombotic thrombocytopenia. There is limited data and lack of substantial evidence regarding transplantation of organs from brain-dead patients with suspected VITT. How to cite this article: Tiwari AM, Zirpe KG, Gurav SK, Bhirud LB, Suryawanshi RS, Kulkarni SS. Case of Suspected SARS-CoV-2 Vaccine-induced Immune Thrombotic Thrombocytopenia: Dilemma for Organ Donation. Indian J Crit Care Med 2022;26(4):514-517.

Indexed as

Cerebral venous sinus thrombosisCOVID vaccineOrgan donationPF4 antibodyThrombocytopeniaVaccine-induced prothrombotic immune thrombocytopenia (VIPIT)Vaccine-induced thrombotic thrombocytopenia (VITT)

Identifiers

PMID35656057
PMCPMC9067495
OpenAlexW4221098048

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.