Evidence map›Paper›PMID 35656034›Full record

ArticleFrontiers in cellular and infection microbiology2022

"Alterations in the Skin Microbiota Are Associated With Symptom Severity in Mycosis Fungoides".

Yumeng Zhang, Lucia Seminario-Vidal, Leah Cohen, Mohammad Hussaini, Jiqiang Yao, David Rutenberg, Youngchul Kim, Anna Giualiano, Lary A Robinson, Lubomir Sokol

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 24 citations in OpenAlex.

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  9. Role of Antigenic Stimulation in Cutaneous T-Cell Lymphomas.The Journal of investigative dermatology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Yumeng ZhangDepartment of Medicine, University of South Florida, Tampa, FL, United States.
Lucia Seminario-VidalDepartment of Cutaneous Oncology, Moffitt Cancer Center, Tampa, FL, United States.
Leah CohenDepartment of Dermatology, University of Pennsylvania, Philadelphia, PA, United States.
Mohammad HussainiDepartment of Pathology, Moffitt Cancer Center, Tampa, FL, United States.
Jiqiang YaoDepartment of Biostatistics and Bioinformatics, Moffitt Cancer Center, Tampa, FL, United States.
David RutenbergDepartment of Medicine, University of South Florida, Tampa, FL, United States.
Youngchul KimDepartment of Biostatistics and Bioinformatics, Moffitt Cancer Center, Tampa, FL, United States.
Anna GiualianoDepartment of Cancer Epidemiology, Moffitt Cancer Center, Tampa, FL, United States.
Lary A RobinsonDepartment of Thoracic Oncology, Moffitt Cancer Center, Tampa, FL, United States.
Lubomir SokolDepartment of Malignant Hematology, Moffitt Cancer Center, Tampa, FL, United States.
Moffitt Cancer Center · USUniversity of South Florida · USUniversity of Pennsylvania · US

Funding

TRANSLATIONAL RESEARCHP30CA076292 · NCI · UNIVERSITY OF SOUTH FLORIDA · PI Christine O'Connell · 1998 to 2026
$93.5M
Infection and Cancer Research: A New Frontier in Cancer Prevention and ControlK05CA181320 · NCI · H. LEE MOFFITT CANCER CTR & RES INST · PI GIULIANO, ANNA R. · 2014 to 2018
$431k
NCI NIH HHS K05 CA181320NCI NIH HHS P30 CA076292
6 · The paper itself

Abstract

Cutaneous T cell lymphoma (CTCL), a non-Hodgkin lymphoma, is thought to arise from mature tissue-resident memory T cells. The most common subtypes include Mycosis Fungoides and Sezary Syndrome. The role of skin microbiota remains unclear in the symptom manifestation of MF. Among 39 patients with MF, we analyzed bacteria colonizing MF lesions and non-lesional skin in the contralateral side and characterized regional changes in the skin microbiota related to MF involvement using the difference in relative abundance of each genus between lesional and contralateral non-lesional skin. We investigated the relationship between these skin microbiota alterations and symptom severity. No statistically significant difference was found in bacterial diversity and richness between lesional and non-lesional skin. Different skin microbiota signatures were associated with different symptoms. More pronounced erythema in the lesions was associated with an increase in

Indexed as

MicrobiotaMycosis FungoidesSezary SyndromeSkin NeoplasmsHumansPilot Projectscutaneous T cell lymphomadisease phenotype associationmicrobiome and dysbiosismycosis fundgoidesskin microbiota

Identifiers

PMID35656034
PMCPMC9152451
OpenAlexW4280563285

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.