Evidence map›Paper›PMID 35655914›Full record

ArticleLancet regional health. Americas2022

Effectiveness of an mHealth intervention to increase adherence to triage of HPV DNA positive women who have performed self-collection (the ATICA study): A hybrid type I cluster randomised effectiveness-implementation trial.

Silvina Arrossi, Melisa Paolino, Victoria Sánchez Antelo, Laura Thouyaret, Racquel E Kohler, Milca Cuberli, Liliana Flores, Verónica Serra, Kasisomayajula Viswanath, Liliana Orellana and 1 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Lancet regional health. Americas, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06500936 (Evaluation of an mHealth Intervention Using an Automated Text Message), which is not on this map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
7.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06500936 nacompletednot on this map

Evaluation of an mHealth Intervention Using an Automated Text Message (SMS) Invitation System to Increase Participation in Mammography Screening Among Women Aged 50-69 Years in the Province of Santa Fe, Argentina

TypeinterventionalSponsorCentro de Estudio de Estado y SociedadRan2021 to 2023Enrolled248ConditionsBreast Cancer ScreeningArmsSMS
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
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  9. Implementation of second round of HPV-based screening for cervical cancer in programmatic contexts in Argentina.Revista panamericana de salud publica = Pan American journal of public health · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 3 countries.

Silvina ArrossiCentro de Estudios de Estado y Sociedad, Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires, Argentina.
Melisa PaolinoCentro de Estudios de Estado y Sociedad, Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires, Argentina.
Victoria Sánchez AnteloCentro de Estudios de Estado y Sociedad, Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires, Argentina.
Laura ThouyaretMinisterio de Salud de la Nación, Argentina.
Racquel E KohlerCancer Health Equity, Cancer Institute of New Jersey, Rutgers - the State University of New Jersey, New Brunswick, USA.
Milca CuberliPrograma Nacional de Prevención de Cáncer Cervicouterino, Instituto Nacional del Cáncer, Buenos Aires, Argentina.
Liliana FloresMinisterio de Salud de la Provincia de Jujuy, San Salvador de Jujuy, Argentina.
Verónica SerraMinisterio de Salud de la Provincia de Jujuy, San Salvador de Jujuy, Argentina.
Kasisomayajula ViswanathDepartment of Social and Behavioral Sciences, Harvard T.H. Chan School of Public Health, Harvard University, Boston, USA.
Liliana OrellanaBiostatistics Unit, Faculty of Health, Deakin University, Geelong, Australia.
ATICA Study team
Consejo Nacional de Investigaciones Científicas y Técnicas · ARNational University of Jujuy · ARDeakin University · AUFundación para la Investigación, Docencia y Prevención del Cáncer · ARHarvard University · USMinisterio de Salud · ARRutgers, The State University of New Jersey · US

Funding

Mixed-Methods approach to evaluate a mHealth intervention to increase adherence to triage of HPV+ women who have performed self-collectionR01CA218306 · NCI · CENTER FOR THE STUDY OF STATE / SOCIETY · PI ARROSSI, SILVINA · 2017 to 2019
$1.1M
NCI NIH HHS R01 CA218306
6 · The paper itself

Abstract

Background: Human Papillomavirus (HPV) self-collection offered by community health workers (CHWs) during home visits has been hampered by low levels of triage Pap among HPV-positive women. We investigated effectiveness of a mHealth intervention to increase adherence to triage Pap. Methods: We conducted a hybrid type I cluster randomised effectiveness-implementation trial in Jujuy, Argentina. CHWs (clusters) were eligible if actively offering HPV self-collection and served at least 26 women aged 30 years and over. Women were eligible if they conducted self-collection and provided a mobile phone number. 260 CHWs were randomly allocated (3:2 ratio) to a multi-component intervention (Up to four SMS messages sent to HPV-positive women, and one SMS message to CHWs to prompt a visit of women with no triage Pap 60 days after a positive-test), or control group (Usual care: Women instructed to attend their health centre 30 days after HPV self-collection to pick-up results). The primary effectiveness outcome was percentage of HPV-positive women with triage 120 days after the HPV-test result. We evaluated implementation of the intervention using the RE-AIM framework. Findings: 221 CHWs (132 intervention, 89 control group) contacted 5389 women; and 5351 agreed to participate (3241 intervention, 2110 control group). In total 314/445 (70·5%) HPV-positive women of the intervention group had triage at 120 days after the HPV result, compared to 163/292 (55·1%) in the control group: 15·5% point improvement; 95%CI: 6·8-24·1; relative risk: 1·28; 95%CI: 1·11-1·48. 97·2% of women accepted the intervention and 86·9% of CHWs agreed to its adoption. Interpretation: The multicomponent mHealth intervention was effective in increasing the percentage of HPV-positive women who had triage Pap, allowing for many more women at risk of cervical cancer to receive timely follow-up. Funding: National Cancer Institute of the National Institutes of Health (USA) under Award Number R01CA218306.

Indexed as

ArgentinaCervical cancerCommunity health workersHPV Self-collectionImplementation SciencemHealthPrevention

Identifiers

PMID35655914
PMCPMC9159703
OpenAlexW4212806213

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.