Evidence map›Paper›PMID 35655905›Full record

ArticleBioinformation2021

Molecular docking analysis of PARγ with compounds from

Ponnulakshmi Rajagopal, Selvaraj Jayaraman, Shazia Fathima Jh, Saravanan Radhakrishnan, Patil Ashlesh Laxman, Vijaya Prakash Krishnan Muthaiah, Satyendra Chandra Tripathi, T S Gugapriya, Aaditya Madhusudan Tarnekar, Gayatri Girish Muthiyan and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioinformation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Anti-Inflammatory Activity of the Constituents from the Leaves ofPharmaceuticals (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Ponnulakshmi RajagopalCentral Research Laboratory, Meenakshi Academy of Higher Education and Research (Deemed to be University), Chennai-600 078, India.
Selvaraj JayaramanDepartment of Biochemistry, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai - 600 077, India.
Shazia Fathima JhDepartment of Oral and Maxillofacial Pathology, Ragas Dental College and Hospitals, Chennai, India.
Saravanan RadhakrishnanDepartment of Biochemistry, Karapaga Vinayaga Institute of Medical and Dental science, Madhuranthagam- 603308, Tamil Nadu, India.
Patil Ashlesh LaxmanDepartment of Physiology, AIIMS, Nagpur 441108, India.
Vijaya Prakash Krishnan MuthaiahDepartment of Rehabilitation Science, School of Public Health and Health professions, 633 Kimball, Buffalo NY, 14214-3079.
Satyendra Chandra TripathiDepartment of Biochemistry, AIIMS, Nagpur 441108, India.
T S GugapriyaDepartment of Anatomy, AIIMS, Nagpur 441108, India.
Aaditya Madhusudan TarnekarDepartment of Anatomy, AIIMS, Nagpur 441108, India.
Gayatri Girish MuthiyanDepartment of Anatomy, AIIMS, Nagpur 441108, India.
Vishwajit Ravindra DeshmukhDepartment of Anatomy, AIIMS, Nagpur 441108, India.
Bharat Ramrao SontakkeDepartment of Anatomy, AIIMS, Nagpur 441108, India.
Kirubhanand ChandrashekarDepartment of Anatomy, AIIMS, Nagpur 441108, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ligand-activated transcription factor peroxisome proliferator-activated receptor (PPAR) has become a major target for type 2 diabetes. It belongs to the nuclear receptor superfamily, which controls the expression of proteins involved in glucose metabolism, lipid metabolism, adipocyte proliferation and differentiation, and insulin sensitivity.

Indexed as

DiabetesMolecular dockingOcimum tenuiflorumProliferator - Activated Receptor - γ

Identifiers

PMID35655905
PMCPMC9148598

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.