Evidence map›Paper›PMID 35655840›Full record

ReviewQuantitative imaging in medicine and surgery2022

Neuroimaging at 7 Tesla: a pictorial narrative review.

Tomohisa Okada, Koji Fujimoto, Yasutaka Fushimi, Thai Akasaka, Dinh H D Thuy, Atsushi Shima, Nobukatsu Sawamoto, Naoya Oishi, Zhilin Zhang, Takeshi Funaki and 5 more

Abstract readReview
In one paragraph

Review in Quantitative imaging in medicine and surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  3. Article
  4. Multiscale characterization of the human claustrum from histology to MRI.Proceedings of the National Academy of Sciences of the United States of America · 2026
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  8. Review
  9. Clinical application ofFrontiers in neuroscience · 2026
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  11. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Tomohisa OkadaHuman Brain Research Center, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Koji FujimotoDepartment of Real World Data Research and Development, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Yasutaka FushimiDepartment of Diagnostic Imaging and Nuclear Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Thai AkasakaHuman Brain Research Center, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Dinh H D ThuyHuman Brain Research Center, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Atsushi ShimaHuman Brain Research Center, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Nobukatsu SawamotoDepartment of Human Health Sciences, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Naoya OishiMedial Innovation Center, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Zhilin ZhangDepartment of Psychiatry, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Takeshi FunakiDepartment of Neurosurgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Yuji NakamotoDepartment of Diagnostic Imaging and Nuclear Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Toshiya MuraiDepartment of Psychiatry, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Susumu MiyamotoDepartment of Neurosurgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Ryosuke TakahashiDepartment of Neurology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Tadashi IsaHuman Brain Research Center, Graduate School of Medicine, Kyoto University, Kyoto, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neuroimaging using the 7-Tesla (7T) human magnetic resonance (MR) system is rapidly gaining popularity after being approved for clinical use in the European Union and the USA. This trend is the same for functional MR imaging (MRI). The primary advantages of 7T over lower magnetic fields are its higher signal-to-noise and contrast-to-noise ratios, which provide high-resolution acquisitions and better contrast, making it easier to detect lesions and structural changes in brain disorders. Another advantage is the capability to measure a greater number of neurochemicals by virtue of the increased spectral resolution. Many structural and functional studies using 7T have been conducted to visualize details in the white matter and layers of the cortex and hippocampus, the subnucleus or regions of the putamen, the globus pallidus, thalamus and substantia nigra, and in small structures, such as the subthalamic nucleus, habenula, perforating arteries, and the perivascular space, that are difficult to observe at lower magnetic field strengths. The target disorders for 7T neuroimaging range from tumoral diseases to vascular, neurodegenerative, and psychiatric disorders, including Alzheimer's disease, Parkinson's disease, multiple sclerosis, epilepsy, major depressive disorder, and schizophrenia. MR spectroscopy has also been used for research because of its increased chemical shift that separates overlapping peaks and resolves neurochemicals more effectively at 7T than a lower magnetic field. This paper presents a narrative review of these topics and an illustrative presentation of images obtained at 7T. We expect 7T neuroimaging to provide a new imaging biomarker of various brain disorders.

Indexed as

7 Tesla (7T)functional magnetic resonance imaging (fMRI)magnetic resonance spectroscopy (MRS)MP2RAGEsusceptibility

Identifiers

PMID35655840
PMCPMC9131333

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.