Evidence map›Paper›PMID 35655788›Full record

ArticleJournal of analytical methods in chemistry2022

Current-Volt Biosensing "Cystatin C" on Carbon Nanowired Interdigitated Electrode Surface: A Clinical Marker Analysis for Bulged Aorta.

Xi Chen, Jie Kang, Qiu Sun, Cheng Liu, Hongling Wang, Chen Wang, Subash C B Gopinath

Open access · goldAbstract read
In one paragraph

Article in Journal of analytical methods in chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 61% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

Xi ChenDepartment of Vascular Surgery, Wuhan No.1 Hospital, WuHan, HuBei 430022, China.
Jie KangDepartment of Vascular Surgery, Liaocheng People's Hospital, Liaocheng, Shandong Province 252000, China.
Qiu SunDepartment of Intervention, Wuhan No. 1 Hospital, Wuhan, Hubei 430022, China.
Cheng LiuDepartment of Vascular Surgery, Nanjing Drum Tower Hospital, The Affiliated of Nanjing University Medical School, Nanjing City, Jiangsu Province 730050, China.
Hongling WangDepartment of Cardiothoracic Surgery, Hospital of Lianqin Security Force 940th, Lanzhou, Gansu 730000, China.
Chen WangDepartment of Peripheral Vascular Intervention, Gansu Provincial Hospital of TCM, No. 418 Guazhou Road, Qilihe District, Lanzhou City, Gansu Province 730050, China.ORCID https://orcid.org/0000-0001-7377-4953
Subash C B GopinathInstitute of Nano Electronic Engineering, Universiti Malaysia Perlis (UniMAP), Kangar 01000, Perlis, Malaysia.ORCID https://orcid.org/0000-0002-8347-4687
Wuhan No.1 Hospital · CNAIMST University · MYGansu Provincial Hospital of TCM · CNLiaocheng People's Hospital · CNNanjing Drum Tower Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A carbon nanowire-modified surface with interdigitated electrode (IDE) sensing system was introduced to identify abdominal aortic aneurysm biomarker "papain," also known as cysteine protease, used as the capture probe to identify Cystatin C. Papain was immobilized through the covalent integration of amine group on papain and the carboxyl group with carbon nanowire. This papain-modified electrode surface was utilized to detect the different concentrations of Cystatin C (100 pg/mL to 3.2 ng/mL). The interaction between papain and Cystatin C was monitored using a picoammeter, and the response curves were compared. With increasing Cystatin C concentrations, the total current levels were gradually increased with a linear range from 200 pg/mL to 3.2 ng/mL, and the current differences were plotted and the detection limit of Cystatin C was calculated as 200 pg/mL. The averaging of three independent experiments (

Identifiers

PMID35655788
PMCPMC9152415
OpenAlexW4281296041

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.