Evidence map›Paper›PMID 35655608›Full record

ArticleHealth systems (Basingstoke, England)2022

Feasibility analysis of a prevention programme for patients with early chronic disease using A mathematical model.

Fanwen Meng, Aidan Lyanzhiang Tan, Bee Hoon Heng, Melvin Khee Shing Leow, Palvannan Kannapiran

Abstract read
In one paragraph

Article in Health systems (Basingstoke, England), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Fanwen MengDepartment of Health Services and Outcomes Research, National Healthcare Group, Singapore.ORCID https://orcid.org/0000-0002-1608-4056
Aidan Lyanzhiang TanPreventive Medicine, National University Hospital, Singapore.
Bee Hoon HengDepartment of Health Services and Outcomes Research, National Healthcare Group, Singapore.
Melvin Khee Shing LeowDepartment of Endocrinology, Tan Tock Seng Hospital, Singapore.
Palvannan KannapiranDepartment of Health Services and Outcomes Research, National Healthcare Group, Singapore.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The increasing prevalence of the chronic disease is of considerable concern to health-care organisations. Prevention programmes to patients with early chronic disease have the potential to improve individual health and quality of life through disease avoidance or delay and to save the medical cost of the health care system. Due to the limited budget in healthcare this study seeks to analyse the feasibility of a programme prior to implementation. A mathematical model is developed to determine incidence reduction rate at which the underlying cost break-even can be achieved; consequently, the programme would be feasible. We show the existence and uniqueness of the underlying incidence reduction and establish the feasibility frontier concerning the trade-offs between intervention effective period and incidence reduction rate. We use a diabetes prevention programme to demonstrate the efficiency and advantage of the model. The proposed model would inform decision-makers scientific principles in determining an intervention for implementation.

Indexed as

chronic diseasecontinuous-time Markov modelCost-benefit analysisprevention programme feasibility

Identifiers

PMID35655608
PMCPMC9154777

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.