ArticleFrontiers in public health2022
Incidence, Risk Factors and Outcomes of Sepsis in Critically Ill Post-craniotomy Patients: A Single-Center Prospective Cohort Study.
Article in Frontiers in public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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8 citing papers in PubMed, 11 citations in OpenAlex.
- A predictive model for the risk of sepsis within 30 days of admission in patients with traumatic brain injury in the intensive care unit: a retrospective analysis based on MIMIC-IV database.European journal of medical research · 2023Trial
- Association of Postoperative Stress Hyperglycemia Ratio with Suspected Infection, Culture Positivity, Sepsis, and Septic Shock in 1408 Patients After Cranial Neurosurgery.Journal of clinical medicine · 2026Article
- Machine Learning Model for Sepsis Prediction in Prolonged and Chronic Critical Illness: Development and Validation Using Retrospective Real-World ICU Data.Journal of clinical medicine · 2026Article
- A predictive model for sepsis risk in patients with non-traumatic cerebral hemorrhage based on the MIMIC-IV database.Scientific reports · 2025Article
- Inpatient neurosurgical mortality in germany: a comprehensive analysis of 2023 in-hospital data.Neurosurgical review · 2025Article
- Identifying early predictive and diagnostic biomarkers and exploring metabolic pathways for sepsis after trauma based on an untargeted metabolomics approach.Scientific reports · 2025Article
- Epidemiology, Risk Factors, and Predictive Modelling of Post-Traumatic Sepsis: A Retrospective Cohort Study.Risk management and healthcare policy · 2025Article
- Diagnostic performance and clinical utility of metagenomic next-generation sequencing in suspected central nervous system infections: a prospective comparative study.Frontiers in cellular and infection microbiology · 2025Article
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Data concerning the epidemiology of sepsis in critically ill post-craniotomy patients are scarce. This study aimed to assess the incidence, risk factors, and outcomes of sepsis in this population. Methods: This was a single-center prospective cohort study. Post-craniotomy patients admitted to the intensive care unit (ICU) were screened daily for the presence of infection and sepsis. Results: Of the 900 included patients, 300 developed sepsis. The cumulative incidence of sepsis was 33.3% [95% confidence interval (CI), 30.2-36.4%]. Advanced age, male, hypertension, trauma, postoperative intracranial complications, and lower Glasgow Coma Scale (GCS) on the first postoperative day were independent risk factors of sepsis. Septic patients had higher hospital mortality (13.7 vs. 8.3%, Conclusion: Sepsis is a frequent complication in critically ill post-craniotomy patients. Advanced age, male, hypertension, trauma, postoperative intracranial complications, and lower GCS on the first postoperative day were independent risk factors of sepsis.
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