Evidence map›Paper›PMID 35655423›Full record

ArticleCancer medicine2023

Evaluation of health behaviors and overall quality of life in younger adult African American cancer survivors.

Matthew R Trendowski, Jaclyn M Kyko, Christine M Lusk, Julie J Ruterbusch, Theresa A Hastert, Felicity W K Harper, Hayley Thompson, Jennifer L Beebe-Dimmer, Ann G Schwartz

Open access · goldAbstract read
In one paragraph

Article in Cancer medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Matthew R TrendowskiDepartment of Oncology, Wayne State University School of Medicine, Detroit, Michigan, USA.ORCID 0000-0001-7006-7065
Jaclyn M KykoDepartment of Oncology, Wayne State University School of Medicine, Detroit, Michigan, USA.
Christine M LuskDepartment of Oncology, Wayne State University School of Medicine, Detroit, Michigan, USA.
Julie J RuterbuschDepartment of Oncology, Wayne State University School of Medicine, Detroit, Michigan, USA.
Theresa A HastertDepartment of Oncology, Wayne State University School of Medicine, Detroit, Michigan, USA.ORCID 0000-0001-6251-6422
Felicity W K HarperDepartment of Oncology, Wayne State University School of Medicine, Detroit, Michigan, USA.
Hayley ThompsonDepartment of Oncology, Wayne State University School of Medicine, Detroit, Michigan, USA.
Jennifer L Beebe-DimmerDepartment of Oncology, Wayne State University School of Medicine, Detroit, Michigan, USA.ORCID 0000-0002-4320-739X
Ann G SchwartzDepartment of Oncology, Wayne State University School of Medicine, Detroit, Michigan, USA.
Wayne State University · US

Funding

Tumor Biology and Microenvironment (Program 1)P30CA022453 · NCI · WAYNE STATE UNIVERSITY · PI Julie Lynn Boerner · 1985 to 2026
$68.4M
The impact of the COVID-19 pandemic on African American cancer survivors and their caregiversU01CA199240 · NCI · WAYNE STATE UNIVERSITY · PI Jennifer L Beebe-Dimmer, Ann G. Schwartz · 2017 to 2026
$15.2M
NCI NIH HHS P30CA022453NCI NIH HHS U01 CA199240
6 · The paper itself

Abstract

backgroundEpidemiological studies of cancer survivors have predominantly focused on non-Hispanic White, elderly patients, despite the observation that African Americans have higher rates of mortality. Therefore, we characterized cancer survivorship in younger African American survivors using the Detroit Research on Cancer Survivors (ROCS) study to assess health behaviors and quality of life.

methodsFive hundred and seventeen patients diagnosed with any cancer between the ages of 20-49 (mean age: 42 years; SD: 6.7 years) completed a survey to identify important clinical, behavioral, and sociodemographic characteristics, measures of health literacy, and experiences of discrimination. Quality of life outcomes were evaluated in patients using FACT-G, FACT-Cog, and PROMIS® Anxiety and Depression scales. Stepwise linear and logistic regression were used to assess the association between quality of life measures and participant characteristics.

resultsThe mean FACT-G score was 74.1 (SD: 21.3), while the FACT-Cog was 55.1 (SD: 17.1) (FACT-G range 0-108 with higher scores indicating better function; elderly cancer patient mean: 82.2; FACT-Cog 18-item range 0-72 points with higher scores indicating better perceived cognitive functioning; scores <54 indicating cognitive impairment). In addition, 27.1% and 21.6% of patients had a score indicative of moderate or severe anxiety and depression, respectively. Perceived discrimination and the number of discriminatory events were significantly associated with reductions in three of the four quality of life measures. Health literacy was positively associated with all four health measures, while total comorbidity count was negatively associated with three of the four measures.

conclusionYounger adult African American cancer survivors who report experiencing discrimination and suffer from multiple comorbid conditions have poorer mental and overall health. Understanding the unique clinical and socioeconomic stressors that influence this patient population is essential for reducing health disparities and improving long-term survivorship.

Indexed as

Cancer SurvivorsNeoplasmsAdultAgedBlack or African AmericanHealth BehaviorHumansMiddle AgedQuality of LifeSurvivorsYoung Adultcancer survivorshipdiscriminationhealth behaviorshealth disparitiesquality of life

Identifiers

PMID35655423
PMCPMC9844626
OpenAlexW4281862959

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.