Evidence map›Paper›PMID 35655422›Full record

ArticleThe Laryngoscope2023

An Ex-vivo Model Examining Acoustics and Aerodynamic Effects Following Medialization With and Without Arytenoid Adduction.

Alexandra Maddox, Liran Oren, Charles Farbos de Luzan, Rebecca Howell, Ephraim Gutmark, Sid Khosla

Open access · hybridAbstract read
In one paragraph

Article in The Laryngoscope, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Vocal Fold Vibratory Kinematics and Acoustic Correlates in Pressed and Breathy Phonation.Journal of speech, language, and hearing research : JSLHR · 2026
    Article
  2. Article
  3. Acoustics and aerodynamic effects following glottal and infraglottal medialization in an excised larynx model.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Alexandra MaddoxDepartment of Aerospace Engineering and Engineering Mechanics, University of Cincinnati, Cincinnati, Ohio, USA.
Liran OrenDepartment of Otolaryngology Head and Neck Surgery, University of Cincinnati, Cincinnati, Ohio, USA.ORCID 0000-0002-3232-6799
Charles Farbos de LuzanDepartment of Otolaryngology Head and Neck Surgery, University of Cincinnati, Cincinnati, Ohio, USA.ORCID 0000-0002-9163-6922
Rebecca HowellDepartment of Otolaryngology Head and Neck Surgery, University of Cincinnati, Cincinnati, Ohio, USA.
Ephraim GutmarkDepartment of Aerospace Engineering and Engineering Mechanics, University of Cincinnati, Cincinnati, Ohio, USA.
Sid KhoslaDepartment of Otolaryngology Head and Neck Surgery, University of Cincinnati, Cincinnati, Ohio, USA.
University of Cincinnati · US

Funding

The Relationships Between Vortices, Acoustics, and Vibration in Vocal Fold AsymmetriesR01DC009435 · NIDCD · UNIVERSITY OF CINCINNATI · PI OREN, LIRAN · 2009 to 2025
$8.5M
NIDCD NIH HHS R01 DC009435
6 · The paper itself

Abstract

objectives/hypothesisQuantify differences in acoustics and intraglottal flow fields between Thyroplasty Type 1 (TT1) with and without arytenoid adduction (AA) using excised canine larynx model. STUDY

designBasic science experiments using excised larynges.

methodsSurgical procedures were implemented in eight excised canine larynges. Acoustics and intraglottal flow measurements were taken at low and high subglottal pressures in each experimental setup.

resultsIn all larynges, vocal efficiency (VE) and cepstrum peak prominence (CPP) were higher, and the mean phonatory flow rate was lower in TT1 with AA than without AA. The glottal asymmetry is reduced with AA and promotes the formation of stronger vortices in the glottal flow during the closing phase of the vibrating folds.

conclusionsFindings suggest a clear acoustic and aerodynamic benefit to the addition of AA when performing TT1. It shows significant improvement in CPP, translating to decreased breathiness and dysphonia and increased VE, leading to easier and more sustainable phonation. Stronger intraglottal vortices are known to be correlated with the loudness of voice produced by phonation. LEVEL OF EVIDENCE: N/A Laryngoscope, 133:621-627, 2023.

Indexed as

LaryngoplastyLarynxVocal Cord ParalysisAcousticsAnimalsArytenoid CartilageDogsGlottisPhonationVocal Cordsarytenoid adductionintraglottal flowmedialization laryngoplastyunilateral vocal fold paralysisvocal efficiency

Identifiers

PMID35655422
PMCPMC9715814
OpenAlexW4281635712

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.