ArticleBMC medicine2022
Associations of handgrip strength with morbidity and all-cause mortality of cardiometabolic multimorbidity.
Article in BMC medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 3 of them syntheses that pooled it.
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Who cites it
45 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Hand Grip Force-Time Curve Indicators Evaluated by Dynamometer: A Systematic Review.Nutrients · 2024Pooled it
- Effects of Upper-Body Plyometric Training on Physical Fitness in Healthy Youth and Young Adult Participants: A Systematic Review with Meta-Analysis.Sports medicine - open · 2023Pooled it
- Pooled it
- Trial
- Associations of cumulative exposure and dynamic trajectories of the combined atherogenic-frailty index with incident cardiometabolic multimorbidity: a prospective cohort study.Journal of global health · 2026Article
- Sex-specific handgrip strength thresholds for short-term mortality risk stratification in Mexican older adults: derivation in MHAS and validation in Mex-Cog.European geriatric medicine · 2026Article
- Associations of Accelerometer-Derived "Weekend Warrior" Physical Activity Pattern With Incident First Cardiometabolic Disease and Cardiometabolic Multimorbidity in Individuals With Hypertension.Journal of the American Heart Association · 2026Article
- Effects of Cacao Flavonoids in Long COVID-19 Patients with Chronic Fatigue: FLALOC, a Placebo-Controlled Randomized Clinical Trial.Journal of clinical medicine · 2026Article
- Reduced handgrip strength and body mass index, gender, and diagnosis are associated with length of stay in hospitalized patients.Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2026Article
- Estimated Cardiorespiratory Fitness and Grip Strength: Independent and Combined Associations With Multimorbidity Risk and Patterns in a Large-Scale Prospective Cohort Study.Journal of the American Heart Association · 2025Article
- Association between relative muscle strength and cardiometabolic multimorbidity in middle-aged and older Chinese adults.Acta diabetologica · 2025Article
- Prevalence and factors associated with cardiometabolic multimorbidity: a cross-sectional study in older adults of the first Brazilian hypertension registry.BMC cardiovascular disorders · 2025Article
- Longitudinal association between body mass index and handgrip strength in community-dwelling older adults: a population-based nationwide cohort study.BMC geriatrics · 2025Article
- Associations of different insulin resistance-related indices with the incidence and progression trajectory of cardiometabolic multimorbidity: a prospective cohort study from UK biobank.Cardiovascular diabetology · 2025Article
- Impact of muscle strength decline and exercise intervention on multimorbidity of chronic diseases in older adults.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2025Review
- Vitamin D status, vitamin D receptor polymorphisms, and risk of cardiometabolic multimorbidity.Nutrition journal · 2025Article
- Normalized Creatinine-to-Cystatin C Ratio and Risk of Cardiometabolic Multimorbidity in Middle-Aged and Older Adults: Insights from the China Health and Retirement Longitudinal Study.Diabetes & metabolism journal · 2025Article
- Transfer Learning Prediction of Early Exposures and Genetic Risk Score on Adult Obesity in Two Minority Cohorts.Prevention science : the official journal of the Society for Prevention Research · 2025Article
- Association between metabolic-associated fatty liver disease and risk of cardiometabolic multimorbidity: a disease trajectory analysis in UK Biobank.Frontiers in endocrinology · 2025Article
- Integrated strategies for type 2 diabetes prevention: The role of diet and exercise.AIMS public health · 2025Review
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
backgroundCardiometabolic multimorbidity (CM) is an increasing public health and clinical concern. However, predictors for the development and prognosis of CM are poorly understood. The aims of this study were to investigate the relation between handgrip strength (HGS) and the risk of CM and to examine the association of HGS with all-cause mortality risk among patients with CM.
methodsThis prospective cohort study involved 493,774 participants from the UK Biobank. CM was defined as the simultaneous occurrence of two or more of the following conditions: type 2 diabetes, stroke, and coronary heart disease (CHD). Cox proportional hazards models were performed to estimate hazard ratios (HRs) and 95% confidence intervals (95% CIs).
resultsDuring a median follow-up of 12.1 years, 4701 incident CM cases were documented among participants with none cardiometabolic disease at baseline. Compared with the fourth quartile (Q4), the multivariable adjusted HR (95% CI) value of Q1 of HGS for developing CM was 1.46 (1.34-1.60). In participants with one cardiometabolic disease at baseline, participants in Q1 of HGS also possessed higher risk of CM than those in Q4, with HRs (95% CIs) being 1.35 (1.23-1.49) in patients with type 2 diabetes, 1.23 (1.04-1.46) in patients with stroke, and 1.23 (1.11-1.36) in patients with CHD. For participants with CM at recruitment, HGS was also associated with the risk of all-cause mortality (Q1 vs. Q4 HR: 1.57, 95% CI: 1.36-1.80).
conclusionsOur study provided novel evidence that HGS could be an independent predictor of morbidity and all-cause mortality of CM.
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