Evidence map›Paper›PMID 35655175›Full record

ArticleBMC pediatrics2022

Gut microbiota and atopic dermatitis in children: a scoping review.

Yue Liu, Xiaofan Du, Shujie Zhai, Xiaodong Tang, Cuiling Liu, Weihong Li

Open access · goldAbstract readScoping Review
In one paragraph

Article in BMC pediatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 2 pooled it
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Skin examination in extreme conditions.Acta biochimica Polonica · 2026
    Review
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  9. Review
  10. Article
  11. Article
  12. Research Progress on the Correlation of Atopic Dermatitis with Gut Microbiota.Clinical, cosmetic and investigational dermatology · 2024
    Review
  13. Article
  14. Article
  15. Article
  16. Atopic Dermatitis: Beyond the Skin and Into the Gut.Journal of clinical medicine · 2023
    Article
  17. Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Yue Liu *Department of Acupuncture and Tuina Science, School of Traditional Chinese Medicine, Naval Medical University, No. 800 Xiangyin Road, Shanghai, 200433, China.
Xiaofan Du *Clinical Medicine Science, Anhui Medical University, Hefei, 230032, China.
Shujie ZhaiDepartment of Acupuncture and Tuina Science, School of Traditional Chinese Medicine, Naval Medical University, No. 800 Xiangyin Road, Shanghai, 200433, China.
Xiaodong TangDepartment of Acupuncture and Tuina Science, School of Traditional Chinese Medicine, Naval Medical University, No. 800 Xiangyin Road, Shanghai, 200433, China.
Cuiling LiuLogistics Service Center, People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi, 830001, China.
Weihong LiDepartment of Acupuncture and Tuina Science, School of Traditional Chinese Medicine, Naval Medical University, No. 800 Xiangyin Road, Shanghai, 200433, China. h82ip7j@163.com.
Anhui Medical University · CNPeople's Hospital of Xinjiang Uygur Autonomous Region · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGut microbiota plays an important role in the development of atopic dermatitis (AD). We aimed to elucidate research trends in gut microbiota and AD in children, to provide evidence and insights to the clinical prevention and treatment of AD in children.

methodsA scoping literature review on the studies of gut microbiota and AD were conducted. Two authors independently searched Pubmed et al. databases for studies focused on gut microbiota and AD in children up to January 15, 2022. The literatures were screened and analyzed by two reviewers.

resultsA total of 44 reports were finally included and analyzed. Current researches have indicated that abnormal human microecology is closely associated with AD, and the disturbance of intestinal microbiota plays an important role in the occurrence and development of AD. Probiotics can correct the microbiota disorder, have the functions of regulating immunity, antioxidant, and help to restore the microecological homeostasis. However, there is still a lack of high-quality research reports on the efficacy and safety of probiotics in the prevention and treatment of AD in children.

conclusionsThe changes of gut microbiota are essential to the development of AD in children, which may be an effective target for the prevention and treatment of AD. Future studies with larger sample size and rigorous design are needed to elucidate the effects and safety of probiotics in AD.

Indexed as

Dermatitis, AtopicGastrointestinal MicrobiomeMicrobiotaProbioticsChildHomeostasisHumansAtopic dermatitisChildrenGut microbiotaPreventionProbioticsReviewTreatment

Identifiers

PMID35655175
PMCPMC9161518
OpenAlexW4281689006

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.