ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2023
Quantitative single photon emission computed tomography derived standardized uptake values on 99mTc-PYP scan in patients with suspected ATTR cardiac amyloidosis.
Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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15 citing papers in PubMed, 16 citations in OpenAlex.
- Agreement between SPECT/CT-derived autoplanar imaging and conventional planar imaging inAnnals of nuclear medicine · 2026Article
- QuantitativeEuropean journal of nuclear medicine and molecular imaging · 2026Article
- Semi-quantitative evaluation of early phaseAnnals of nuclear medicine · 2026Article
- Article
- Multimodal Imaging Evaluation of Myocardial Involvement in Rare Oculoleptomeningeal Hereditary Transthyretin Amyloidosis.JACC. Case reports · 2025Article
- Myocardium-to-cavity ratio derived from simultaneousEJNMMI reports · 2025Article
- The Accuracy of Technetium-99 m Pyrophosphate Imaging in Diagnosing Transthyretin Cardiac Amyloidosis and Its Impact on Patient Management.Current cardiology reports · 2025Review
- DPD Quantification Correlates With Extracellular Volume and Disease Severity in Wild-Type Transthyretin Cardiac Amyloidosis.JACC. Advances · 2024Article
- Current status and perspectives of nuclear cardiology.Annals of nuclear medicine · 2024Review
- Transthyretin amyloid cardiomyopathy disease burden quantified usingJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023Article
- Response to letter to the editor.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023Article
- Using standardized uptake values in pyrophosphate imaging.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023Article
- Quantitative SPECT/CT Parameters in the Assessment of Transthyretin Cardiac Amyloidosis-A New Dimension of Molecular Imaging.Journal of cardiovascular development and disease · 2023Review
- Towards a Diagnosis of Cardiac Amyloidosis: Single Center Experience withMedicina (Kaunas, Lithuania) · 2023Review
- Quantitation in ATTR cardiac amyloidosis: the next step is almost there!Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023Article
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15 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
Technetium-99 pyrophosphate scintigraphy (99mTc-PYP) provides qualitative and semiquantitative diagnosis of ATTR cardiac amyloidosis (ATTR-CA) using the Perugini scoring system and heart/contralateral heart ratio (H/CL) on planar imaging. Standardized uptake values (SUV) with quantitative single photon emission computed tomography (xSPECT/CT) can offer superior diagnostic accuracy and quantification through precise myocardial contouring that enhances assessment of ATTR-CA burden. We examined the correlation of xSPECT/CT SUVs with Perugini score and H/CL ratio. We also assessed SUV correlation with cardiac magnetic resonance (CMR), echocardiographic, and baseline clinical characteristics. Retrospective review of 78 patients with suspected ATTR-CA that underwent 99mTc-PYP scintigraphy with xSPECT/CT. Patients were grouped off Perugini score (Grade 0-1 and Grade 2-3), H/CL ratio (≥ 1.5 and < 1.5). Two cohorts were also created: myocardium SUV
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