Evidence map›Paper›PMID 35655076›Full record

ArticleScientific reports2022

Midtrimester cervical elastography in pregnant women with a history of loop electrosurgical excision procedure (LEEP).

Hyun-Hwa Cha, Won Joon Seong, Hyun Mi Kim, Hyun-Joo Seol, Ji-Hee Sung, Hyun Soo Park, Han-Sung Hwang, Hayan Kwon, Yun Ji Jung, Ja-Young Kwon and 1 more

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 1 country.

Hyun-Hwa Cha *Department of Obstetrics and Gynecology, School of Medicine, Kyungpook National University Chilgok Hospital, Kyungpook National University, Daegu, Korea.
Won Joon Seong *Department of Obstetrics and Gynecology, School of Medicine, Kyungpook National University Chilgok Hospital, Kyungpook National University, Daegu, Korea.
Hyun Mi KimDepartment of Obstetrics and Gynecology, School of Medicine, Kyungpook National University Chilgok Hospital, Kyungpook National University, Daegu, Korea.
Hyun-Joo SeolDepartment of Obstetrics and Gynecology, Kyung Hee University School of Medicine, Seoul, Korea.
Ji-Hee SungDepartment of Obstetrics and Gynecology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul, 06351, Korea.
Hyun Soo ParkDepartment of Obstetrics and Gynecology, Graduate School of Medicine, Dongguk University, Goyang, Korea.
Han-Sung HwangDepartment of Obstetrics and Gynecology, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, Korea.
Hayan KwonDepartment of Obstetrics and Gynecology, Institute of Women's Life Medical Science, Yonsei University College of Medicine, Seoul, Korea.
Yun Ji JungDepartment of Obstetrics and Gynecology, Institute of Women's Life Medical Science, Yonsei University College of Medicine, Seoul, Korea.
Ja-Young KwonDepartment of Obstetrics and Gynecology, Institute of Women's Life Medical Science, Yonsei University College of Medicine, Seoul, Korea.
Soo-Young OhDepartment of Obstetrics and Gynecology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul, 06351, Korea. ohsymd@skku.edu.
Kyungpook National University Hospital · KRYonsei University · KRDongguk University · KRKonkuk University Medical Center · KRKyung Hee University · KRSamsung Medical Center · KRSungkyunkwan University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We aimed to compare cervical elastographic parameters based on a previous loop electrosurgical excision procedure (LEEP) and to determine whether they can predict preterm delivery in pregnant women with a history of LEEP. This multicenter prospective case-control study included 71 singleton pregnant women at 14-24 weeks of gestation with a history of LEEP and 1:2 gestational age-matched controls. We performed cervical elastography using E-cervix and compared maternal characteristics, delivery outcomes, cervical length (CL), and elastographic parameters between the two groups. The median mid-trimester CL was significantly shorter in the LEEP group. Most elastographic parameters, including internal os (IOS), external os (EOS), elasticity contrast index (ECI), and hardness ratio (HR), were significantly different in the two groups. In the LEEP group, the sPTD group compared to the term delivery (TD) group showed a higher rate of previous sPTD (50% vs. 1.7%, p < 0.001), higher IOS and ECI (IOS: 0.28 [0.12-0.37] vs. 0.19 [0.10-0.37], p = 0.029; ECI: 3.89 [1.79-4.86] vs. 2.73 [1.48-5.43], p = 0.019), and lower HR (59.97 [43.88-92.43] vs. 79.06 [36.87-95.40], p = 0.028), but there was no significant difference in CL (2.92 [2.16-3.76] vs. 3.13 [1.50-3.16], p = 0.247). In conclusion, we demonstrated that a history of LEEP was associated with a change in cervical strain measured in mid-trimester as well as with CL shortening. We also showed that cervical elastography can be useful in predicting sPTD in pregnant women with previous LEEP.

Indexed as

Cervix UteriElasticity Imaging TechniquesCase-Control StudiesElectrosurgeryFemaleHumansInfant, NewbornPregnancyPregnancy Trimester, SecondPregnant People

Identifiers

PMID35655076
PMCPMC9163180
OpenAlexW4281673517

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.