Evidence map›Paper›PMID 35655069›Full record

ArticleScientific reports2022

Age and sex influence the response in lipid metabolism of dehydrated Wistar rats.

S Quirós Cognuck, W L Reis, M S Silva, S V Zorro, G Almeida-Pereira, L K Debarba, L L K Elias, J Antunes-Rodrigues

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Variability in Oxytocin Blood Levels in Rats: A Review and Experimental Insights.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

S Quirós CognuckPhysiology Department, Ribeirao Preto Medicine School, University of Sao Paulo, Ribeirao Preto, Sao Paulo, 14049-900, Brazil. susana.cognuck@gmail.com.
W L ReisDepartment of Physiological Science, Center of Biological Sciences, Federal University of Santa Catarina, Florianópolis, SC, 88040-900, Brazil.
M S SilvaPhysiology Department, Ribeirao Preto Medicine School, University of Sao Paulo, Ribeirao Preto, Sao Paulo, 14049-900, Brazil.
S V ZorroMedical Clinic Department, Ribeirao Preto Medicine School, University of Sao Paulo, Ribeirao Preto, Sao Paulo, 14048-900, Brazil.
G Almeida-PereiraPhysiology Department, Ribeirao Preto Medicine School, University of Sao Paulo, Ribeirao Preto, Sao Paulo, 14049-900, Brazil.
L K DebarbaPhysiology Department, Ribeirao Preto Medicine School, University of Sao Paulo, Ribeirao Preto, Sao Paulo, 14049-900, Brazil.
L L K EliasPhysiology Department, Ribeirao Preto Medicine School, University of Sao Paulo, Ribeirao Preto, Sao Paulo, 14049-900, Brazil.
J Antunes-RodriguesPhysiology Department, Ribeirao Preto Medicine School, University of Sao Paulo, Ribeirao Preto, Sao Paulo, 14049-900, Brazil.
Universidade de São Paulo · BRUniversidade Federal de Santa Catarina · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aging is associated a decrease in thirst sensation, which makes old people more susceptible to dehydration. Dehydration produces energy metabolism alterations. Our objective was to determinate the effect of water deprivation (WD) in the lipid metabolism of old male and female rats. Here we show that in the state of WD, aging and sex alters retroperitoneal white adipose tissue (R-WAT) weight of rats, WD old female rats had more lipolysis products than old male rats, a sexual dimorphism in the hormonal response related with metabolism of the adipose tissue of old rats during WD, the expression of P-para mRNA in R-WAT did not present any alteration in animals submitted to WD, the expression of Aqp7 mRNA in R-WAT is altered by WD, age, and sex. Also, WD stimulated an increase in the plasma concentration of oxytocin and the expression of mRNA of the oxytocin receptors in R-WAT.

Indexed as

DehydrationLipid MetabolismAdipose Tissue, WhiteAnimalsFemaleHumansMaleRatsRats, WistarRNA, MessengerRNA, Messenger

Identifiers

PMID35655069
PMCPMC9163080
OpenAlexW4281626410

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.