Evidence map›Paper›PMID 35655053›Full record

ReviewMolecular biology reports2022

Exosomal long noncoding RNAs - the lead thespian behind the regulation, cause and cure of autophagy-related diseases.

Sougata Ghosh Chowdhury, Debalina Bhattacharya, Parimal Karmakar

Abstract readReview
PubMed Publisher
In one paragraph

Review in Molecular biology reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sougata Ghosh ChowdhuryDepartment of Life Science and Biotechnology, Jadavpur University, 700032, Kolkata, India.
Debalina BhattacharyaDepartment of Microbiology, Maulana Azad College, 700013, Kolkata, India.
Parimal KarmakarDepartment of Life Science and Biotechnology, Jadavpur University, 700032, Kolkata, India. pkarmakar_28@yahoo.co.in.ORCID http://orcid.org/0000-0002-9423-9906

Funding

Department of Science and Technology, Government of West Bengal (BT/ST/P/S7T/2G-13/2017),
6 · The paper itself

Abstract

Recent advances in exosome biology have revealed significant roles of exosome and their contents in intercellular communication. Among various exosomal content, long non-coding RNAs (lncRNAs), which have a large size (˃ 200 nt) and lack protein coding potential, are known to play key roles in intercellular communication and novel biomarkers of various metabolic disorders. Moreover, long non-coding RNAs are often involved in the regulation of various cellular processes such as autophagy, apoptosis, cell proliferation. On the other hand, autophagy is the central regulating point that controls the various metabolic functions of the body. This process is known to prevent diseases and promote longevity. Therefore, the present review discusses the relationship between diseases and autophagy, and also look into the biological functions of exosome-associated lncRNAs in regulating autophagy. Furthermore, this review will summarize some of the studies that provide novel insights into the pathogenesis of autophagy-related diseases followed by the non-canonical roles played by autophagy and related proteins in the development of exosome biogenesis.

Indexed as

ExosomesRNA, Long NoncodingApoptosisAutophagyCell CommunicationRNA, Long NoncodingAutophagyAutophagy related diseasesExosomeLong non-coding RNAs (lncRNAs)

Identifiers

PMID35655053

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.