Evidence map›Paper›PMID 35654917›Full record

ReviewClinical rheumatology2022

Amiodarone-induced cutaneous leukocytoclastic vasculitis: a case report and a review of the literature.

Tumay Ak, Rumeysa Nur Algan, Senay Agirgol, Seyhan Ozakkayunlu Hascicek, Zafer Turkoglu

Abstract readCase ReportsReview
PubMed Publisher
In one paragraph

Review in Clinical rheumatology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Tumay AkCerrahpasa Medical Faculty, Department of Internal Medicine, Istanbul University-Cerrahpasa, Istanbul, Turkey. tumayyakk@gmail.com.ORCID http://orcid.org/0000-0002-1548-7638
Rumeysa Nur AlganDepartment of Dermatology, Basaksehir Cam and Sakura City Hospital, Istanbul, Turkey.ORCID http://orcid.org/0000-0002-2439-4046
Senay AgirgolDepartment of Dermatology, Basaksehir Cam and Sakura City Hospital, Istanbul, Turkey.ORCID http://orcid.org/0000-0002-8000-8883
Seyhan Ozakkayunlu HascicekDepartment of Pathology, Sisli Etfal Training and Research Hospital, Istanbul, Turkey.ORCID http://orcid.org/0000-0002-3243-8811
Zafer TurkogluDepartment of Dermatology, Basaksehir Cam and Sakura City Hospital, Istanbul, Turkey.ORCID http://orcid.org/0000-0002-4357-6646
Istanbul Metropolitan Municipality · TRIstanbul University-Cerrahpaşa · TRŞişli Etfal Eğitim ve Araştırma Hastanesi · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Amiodarone can be used in a variety of arrhythmias. Given its widespread use, the probability of clinicians encountering its cutaneous adverse effects is high. A few cases of amiodarone-induced cutaneous vasculitis were reported in the literature, probably because it is underdiagnosed in clinical practice. Indeed, amiodarone-related cutaneous reactions may present a wide range of manifestations and are sometimes difficult to diagnose. Herein, we report a case with a sizeable necrotic ulcer on the left lower leg shortly after amiodarone exposure. A rigorous diagnostic study was performed before concluding the diagnosis of amiodarone-induced cutaneous vasculitis, which showed the histopathological features of leukocytoclastic vasculitis. The lesion was almost completely healed by the third month of discontinuation of amiodarone. We did a literature search and found seven cases which were reported as leukocytoclastic or lymphocytic vasculitis. We reviewed previous cases and presented our case in comparison to prior cases.

Indexed as

AmiodaroneVasculitis, Leukocytoclastic, CutaneousArrhythmias, CardiacHumansLegSkinAmiodaroneAdverse effectsAmiodaroneLeukocytoclastic vasculitisSkin ulcer

Identifiers

PMID35654917
OpenAlexW4281704160

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.