Evidence map›Paper›PMID 35653755›Full record

ArticleJournal of psychopathology and clinical science2022

Intergenerational transmission of depressive and anxiety disorders: Mediation via youth personality.

Daniel M Mackin, Megan C Finsaas, Brady D Nelson, Greg Perlman, Roman Kotov, Daniel N Klein

Open access · hybridAbstract read
In one paragraph

Article in Journal of psychopathology and clinical science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Daniel M MackinDepartment of Psychology.ORCID 0000-0002-2188-2968
Megan C FinsaasDepartment of Epidemiology.ORCID 0000-0001-8290-7500
Brady D NelsonDepartment of Psychology.ORCID 0000-0003-3214-8977
Greg PerlmanDepartment of Psychiatry.
Roman KotovDepartment of Psychology.
Daniel N KleinDepartment of Psychology.

Funding

Temperamental Low PE in Preschoolers and Depression RiskR01MH069942 · NIMH · STATE UNIVERSITY NEW YORK STONY BROOK · PI KLEIN, DANIEL N · 2004 to 2023
$14.2M
RESEARCH TRAINING PROGRAM IN PSYCHIATRIC EPIDEMIOLOGYT32MH013043 · NIMH · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI Katherine M. Keyes · 1985 to 2026
$11.7M
Personality Development and Vulnerability to First-Episode DepressionR01MH093479 · NIMH · STATE UNIVERSITY NEW YORK STONY BROOK · PI KOTOV, ROMAN I · 2012 to 2016
$3.3M
Developmental pathways model of depression heterogeneityR01MH133652 · NIMH · STATE UNIVERSITY NEW YORK STONY BROOK · PI Daniel N Klein, Roman I Kotov · 2024 to 2026
$2.4M
NIMH NIH HHS R01 MH069942NIMH NIH HHS R01 MH093479NIMH NIH HHS R01 MH133652NIMH NIH HHS T32 MH013043
6 · The paper itself

Abstract

Youth personality is hypothesized to mediate the intergenerational transmission of internalizing disorders. However, this has rarely been examined. We tested whether the intergenerational transmission of depressive and anxiety disorders is mediated by youth neuroticism and extraversion, and how parent personality influenced these relationships. Participants included 550 adolescent girls, aged 13-15 years at baseline (T1), and a coparticipating biological parent. Depressive and anxiety disorders were assessed by interview at T1, and adolescents were reinterviewed every 9 months for 3 years (T2-T5). Parent and youth personality was assessed at T1. Four path models examined direct and indirect effects of parent psychopathology and personality (neuroticism and extraversion) on youth outcomes, with youth neuroticism and extraversion as mediators in separate models. In the model examining the effects of parent psychopathology via T1 youth neuroticism, there were direct effects of parent depression on T2-T5 youth depressive disorders and indirect effects of parent anxiety disorders on T2-T5 youth depressive and anxiety disorders. When parent neuroticism was added, indirect effects of T1 parent anxiety disorders and neuroticism on T2-T5 youth depressive and anxiety disorders via T1 youth neuroticism were significant. In the model examining T1 youth extraversion as a mediator, there were significant direct effects of parent depressive and anxiety disorders on T2-T5 youth depressive and anxiety disorders, respectively. Finally, when adding parent extraversion, indirect effects of parent extraversion on T2-T5 youth depressive and anxiety disorders via youth extraversion were significant. Parent and youth personality play important roles in the intergenerational transmission of depressive and anxiety disorders. (PsycInfo Database Record (c) 2022 APA, all rights reserved).

Indexed as

Anxiety DisordersExtraversion, PsychologicalAdolescentFemaleHumansPersonalityPersonality DisordersPersonality Inventory

Identifiers

PMID35653755
PMCPMC9292465
OpenAlexW4281627857

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.