ArticleCancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology2022
The Association between Smoking and Anal Human Papillomavirus in the HPV Infection in Men Study.
Article in Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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Who cites it
11 citing papers in PubMed, 16 citations in OpenAlex.
- High prevalence of anal HPV16 infection among HIV-negative men who have sex with men and transgender women using pre-exposure prophylaxis: a single-centre retrospective cross-sectional study.New microbes and new infections · 2026Article
- Emotional support networks and discussion of anal cancer among sexual minority men in Nigeria: insights from an ego-centric analysis.BMC public health · 2026Article
- Tobacco-associated carcinogenesis with nicotine-mediated tumor promotion across the gastrointestinal tract: A narrative review.Tobacco prevention & cessation · 2026Review
- The Association Between Alcohol Consumption and Anal Human Papillomavirus in the HPV Infection in Men Study.medRxiv : the preprint server for health sciences · 2025Article
- Emerging paradigms: unmasking the role of oxidative stress in HPV-induced carcinogenesis.Infectious agents and cancer · 2024Review
- Population-level incidence of human papillomavirus-positive oropharyngeal, cervical, and anal cancers, by smoking status.Journal of the National Cancer Institute · 2024Article
- HPV Infection of the Oropharyngeal, Genital and Anal Mucosa and Associated Dysplasia in People Living with HIV.Viruses · 2023Article
- State Variation in Squamous Cell Carcinoma of the Anus Incidence and Mortality, and Association With HIV/AIDS and Smoking in the United States.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2023Article
- Tobacco Smoking and Gastrointestinal Cancer Risk.Visceral medicine · 2022Review
- Factors affecting HPV infection in U.S. and Beijing females: A modeling study.Frontiers in public health · 2022Article
- HPV Prevention in Men: A Narrative Review of Strategies, Risks, and Public Health Implications.American journal of men's healthReview
Corrections and comments
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Authors and funding
8 authors at 6 institutions in 3 countries.
Funding
Abstract
backgroundPrevious studies show an association between smoking and anal cancer. The objective of this study was to assess the association between smoking and anal HPV (human papillomavirus) prevalence, incidence, and persistence in men.
methodsThe HPV Infection in Men (HIM) Study is a multinational study that enrolled HIV-negative men. At baseline and follow-up visits, anal specimens were collected. HPV genotyping was assessed by linear array. Prevalence ratios (PR) were used to assess the association between smoking and anal HPV prevalence. Odds ratios (OR) were used to assess the association between smoking and anal HPV incidence and ≥12-months persistence.
resultsCurrent smokers have a higher prevalence [adjusted PR (aPR), 1.36; 95% confidence interval (CI), 1.06-1.73) and incidence [adjusted OR (aOR), 1.74; 95% CI, 1.26-2.39] and ≥12-months persistence (aOR, 1.67; 95% CI, 1.19-2.33) of any anal HPV compared with never smokers. There were no differences in the prevalence, incidence, or persistence of anal HPV between former and never smokers. Smoking status was not associated with the prevalence or persistence of anal HPV among men who have sex with men but was associated with higher incidence of HR-HPV. Among men that have sex with women (MSW), current smokers had an increased prevalence and incidence of LR-HPV compared with never smokers.
conclusionsCurrent smokers had a higher prevalence, persistence, and incidence of HPV compared with never smokers. Further research is needed to assess the role smoking in anal HPV persistence and progression to disease. IMPACT: Prevention initiatives should raise awareness about smoking and the risk factor of anal HPV infection and anal cancer.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.