Evidence map›Paper›PMID 35653696›Full record

Trial reportInternational journal of epidemiology2022

A secondary data analysis of a cluster randomized controlled trial: improved cookstoves associated with reduction in incidence of low birthweight in rural Malawi.

Rebecca Best, Jullita Malava, Albert Dube, Cynthia Katundu, Fredrick Kalobekamo, Kevin Mortimer, Stephen B Gordon, Moffat Nyirenda, Amelia Crampin, Estelle McLean

Open access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in International journal of epidemiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 60% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Rebecca BestLondon School of Hygiene and Tropical Medicine, London, UK.
Jullita MalavaMalawi Epidemiology and Intervention Research Unit, Karonga, Malawi.
Albert DubeMalawi Epidemiology and Intervention Research Unit, Karonga, Malawi.
Cynthia KatunduMalawi Epidemiology and Intervention Research Unit, Karonga, Malawi.
Fredrick KalobekamoMalawi Epidemiology and Intervention Research Unit, Karonga, Malawi.
Kevin MortimerLiverpool School of Tropical Medicine, Liverpool, UK.
Stephen B GordonMalawi Liverpool Wellcome Trust, Blantyre, Malawi.
Moffat NyirendaLondon School of Hygiene and Tropical Medicine, London, UK.ORCID 0000-0003-2120-4806
Amelia CrampinLondon School of Hygiene and Tropical Medicine, London, UK.
Estelle McLeanLondon School of Hygiene and Tropical Medicine, London, UK.
London School of Hygiene & Tropical Medicine · GBMalawi Epidemiology and Intervention Research Unit · MWLiverpool School of Tropical Medicine · GBUniversity of Liverpool · GB

Funding

Medical Research Council MR/K006533/1Medical Research Council MR/L002515/1Wellcome Trust
6 · The paper itself

Abstract

backgroundIn northern rural Malawi, the majority of households cook using open fires and there is also a high burden of adverse birth outcomes. The use of open fires or highly polluting cookstoves is associated with low birthweight in babies. There is mixed evidence on whether implementation of cleaner burning cookstoves reduces the number of babies born with low birthweight.

methodsThis is a secondary analysis of a cluster randomized control trial in Malawi, conducted over 2014-17. Households were randomized to receive improved cookstoves or to continue current practices. For this analysis, the primary outcome was low birthweight in households under routine demographic surveillance, among births occurring within the trial time frame (N = 4010). A subset of data with stricter exposure definitions respecting the original randomized allocation was also analysed (N = 1050). A causal, forwards modelling approach was used.

resultsThe main dataset showed evidence of effect of the intervention on low birthweight [adjusted odds ratio (aOR) 0.69; 95% CI 0.48-0.99, n = 2788). The subset analysis lacked power to provide evidence of association between improved cookstoves and low birthweight in the stricter exposure definition (aOR 0.62; 95% CI 0.35-1.09, n = 932).

conclusionsThis study provides some evidence that an improved cookstove intervention in rural Malawi reduced the number of babies born with low birthweight by 30%. This direction of the effect was also seen in the subset analysis. The analysis suggests that the intervention reduced the number of infants born prematurely or with intra-uterine growth restriction, indicating that improved cookstoves could be a useful maternal health intervention.

Indexed as

Air Pollution, IndoorBirth WeightCookingHumansIncidenceInfantMalawibirth outcomesbirthweightcookstovehousehold pollutionMaternal healthneonatal health

Identifiers

PMID35653696
PMCPMC9749713
OpenAlexW4281808796

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.