Evidence map›Paper›PMID 35653581›Full record

ArticleAngewandte Chemie (International ed. in English)2022

Umpolung Ala

Feng Zhu, Eric Miller, Wyatt C Powell, Kelly Johnson, Alexander Beggs, Garrett E Evenson, Maciej A Walczak

Open access · greenAbstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Peptide Boronic Acids by Late-Stage Hydroboration on the Solid Phase.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  5. Article
  6. Desulfurative Borylation of Small Molecules, Peptides, and Proteins.Journal of the American Chemical Society · 2023
    Article
  7. Article
  8. Chemical science · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Feng ZhuFrontiers Science Center for Transformative Molecules, Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs, School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University, Shanghai, 200240, China.
Eric MillerDepartment of Chemistry, University of Colorado, Boulder, CO 80309, USA.
Wyatt C PowellDepartment of Chemistry, University of Colorado, Boulder, CO 80309, USA.
Kelly JohnsonDepartment of Chemistry, University of Colorado, Boulder, CO 80309, USA.
Alexander BeggsDepartment of Chemistry, University of Colorado, Boulder, CO 80309, USA.
Garrett E EvensonDepartment of Chemistry, University of Colorado, Boulder, CO 80309, USA.
Maciej A WalczakDepartment of Chemistry, University of Colorado, Boulder, CO 80309, USA.ORCID 0000-0002-8049-0817
University of Colorado Boulder · USShanghai Jiao Tong University · CN

Funding

Synthesis and Chemical Biology of Thiopeptide AntibioticsR01GM138682 · NIGMS · UNIVERSITY OF COLORADO · PI WALCZAK, MACIEJ · 2021 to 2024
$1.4M
NIGMS NIH HHS R01 GM138682
6 · The paper itself

Abstract

Non-proteogenic amino acids and functionalized peptides are important motifs in modern drug discovery. Here we report that Ala

Indexed as

Amino AcidsPeptidesIndicators and ReagentsPeptides, CyclicProteinsSolid-Phase Synthesis TechniquesAmino AcidsIndicators and ReagentsPeptidesPeptides, CyclicProteinsAlaBBoronoalanineMacrocyclizationNon-Proteogenic Amino AcidsPeptides

Identifiers

PMID35653581
PMCPMC9329247
OpenAlexW4281720635

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.