Evidence map›Paper›PMID 35653550›Full record

ArticleEnvironmental science & technology2022

Vesicle-Cloaked Rotavirus Clusters are Environmentally Persistent and Resistant to Free Chlorine Disinfection.

Mengyang Zhang, Sourish Ghosh, Mengqiao Li, Nihal Altan-Bonnet, Danmeng Shuai

Open access · greenAbstract read
In one paragraph

Article in Environmental science & technology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
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  4. Virion aggregation shapes infection dynamics and evolutionary potential.bioRxiv : the preprint server for biology · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Mengyang ZhangDepartment of Civil and Environmental Engineering, The George Washington University, Washington, District of Columbia 20052, United States.
Sourish GhoshLaboratory of Host-Pathogen Dynamics, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland 20892, United States.
Mengqiao LiDepartment of Civil and Environmental Engineering, The George Washington University, Washington, District of Columbia 20052, United States.ORCID 0000-0002-0567-9716
Nihal Altan-BonnetLaboratory of Host-Pathogen Dynamics, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland 20892, United States.
Danmeng ShuaiDepartment of Civil and Environmental Engineering, The George Washington University, Washington, District of Columbia 20052, United States.ORCID 0000-0003-3817-4092
National Institutes of Health · USGeorge Washington University · US

Funding

Virus Egress PathwaysZIAHL006234 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI ALTAN-BONNET, NIHAL · 2017 to 2025
$21.8M
Vesicle-Cloaked Virus Clusters as Emerging Pathogens: Will They Challenge Current Disinfection Paradigm?R21AI154049 · NIAID · GEORGE WASHINGTON UNIVERSITY · PI SHEN, YUN, SHUAI, DANMENG · 2021 to 2022
$490k
NIAID NIH HHS R21 AI154049
6 · The paper itself

Abstract

Recent discovery of vesicle-cloaked virus clusters (i.e., viral vesicles) has greatly challenged the central paradigm of viral transmission and infection as a single virion. To understand the environmental transmission of viral vesicles, we used an in vivo model to investigate their environmental persistence and engineering control by disinfection. Murine rotavirus vesicles maintained both their integrity and infectivity after incubation in filtered freshwater and wastewater for at least 7 days, with 24.5-27.5% of the vesicles still intact at 16 weeks after exposure to both waters. Free chlorine disinfection at a dosage of 13.3 mg min L

Indexed as

RotavirusAnimalsChlorineDisinfectionFecesMiceWastewaterChlorineWastewaterenvironmental persistencefree chlorine disinfectionrotavirusvesicle-cloaked virus clusters

Identifiers

PMID35653550
PMCPMC9472322
OpenAlexW4281668403

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.