ArticleScience immunology2022
Immune memory to SARS-CoV-2 Omicron BA.1 breakthrough infections: To change the vaccine or not?
Article in Science immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed.
- Ultra-Sensitive 3D Lateral Flow Assay Device for SARS-CoV-2 Detection Based on One-Step Dual-Signal Amplification.Analytical chemistry · 2025Article
- Maternal Preconception COVID-19 Vaccination and Its Protective Effect on Infants after a Breakthrough Infection during Pregnancy.Vaccines · 2024Article
- SARS-CoV-2 BA.1 and BA.2 breakthrough infections boost antibody responses to early Omicron subvariants but not BQ.1.1 or XBB.1.5.Cell reports. Medicine · 2024Article
- Intradermal Fractional ChAdOx1 nCoV-19 Booster Vaccine Induces Memory T Cells: A Follow-Up Study.Vaccines · 2024Article
- Survey of white-footed mice (Peromyscus leucopus) in Connecticut, USA reveals low SARS-CoV-2 seroprevalence and infection with divergent betacoronaviruses.Npj viruses · 2023Article
- Trends of humoral immune responses to heterologous antigenic exposure due to vaccination & omicron SARS-CoV-2 infection: Implications for boosting.The Indian journal of medical research · 2023Observational
- Omicron variants breakthrough infection elicited higher specific memory immunity than third dose booster in healthy vaccinees.Virologica Sinica · 2023Article
- Article
- Three-dose vaccination-induced immune responses protect against SARS-CoV-2 Omicron BA.2: a population-based study in Hong Kong.The Lancet regional health. Western Pacific · 2023Article
- Vaccine-elicited B and T cell immunity to SARS-CoV-2 is impaired in chronic lung disease patients.medRxiv : the preprint server for health sciences · 2023Article
- Hybrid Immunity to SARS-CoV-2 from Infection and Vaccination-Evidence Synthesis and Implications for New COVID-19 Vaccines.Biomedicines · 2023Review
- Viable SARS-CoV-2 Omicron sub-variants isolated from autopsy tissues.Frontiers in microbiology · 2023Article
- Computational investigation of natural compounds as potential main protease (MComputers in biology and medicine · 2022Article
- Antigenic sin of wild-type SARS-CoV-2 vaccine shapes poor cross-neutralization of BA.4/5/2.75 subvariants in BA.2 breakthrough infections.Nature communications · 2022Article
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Analysis of memory B cell responses to Spike antigen after Omicron BA.1 breakthrough infections suggests that "original antigenic sin" is in play.
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Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.