ArticlePloS one2022
Weight gain after renal transplant: Incidence, risk factors, and outcomes.
Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 30 citations in OpenAlex.
- Feasibility, Acceptability, and Satisfaction of a Lifestyle Intervention for Post-Transplant Weight Loss.Transplantation proceedings · 2025Trial
- Trajectory-based weight modeling distinguishes pathologic weight loss and predicts adverse events in nonhuman primate allogeneic kidney transplantation.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2026Article
- From Continuous-Flow Mechanical Circulatory Support to Heart Transplantation: Hemodynamic, Immunometabolic, and Body Composition Determinants of Rehabilitation Outcomes.Journal of clinical medicine · 2026Review
- CT-Derived Body Composition and Diet Quality in Kidney Transplant Recipients: A Single-Center Retrospective Cross-Sectional Study.Medicina (Kaunas, Lithuania) · 2026Article
- Changes in Body Composition Compartments After Kidney Transplantation: A One-Year Prospective Study.Journal of clinical medicine · 2025Article
- Posttransplant diabetes mellitus and long-term outcomes after kidney transplantation in a steroid avoidance regimen: a cohort study.BMC nephrology · 2025Article
- Review
- Transplant Outcomes and Weight Management in Renal Disease Study.Indian journal of transplantation · 2025Article
- Diabetes Mellitus in Kidney Transplant Recipients and New Hypoglycemic Agent Options.International journal of molecular sciences · 2025Review
- Combined Body Mass Index and Body Surface Area to Predict Post Kidney Transplant Outcomes in Patients With Obesity.Transplantation direct · 2025Article
- Incidence and Risk Factors of Obesity and Overweight in Kidney Transplant Recipients and Their Effect on Graft Outcome.Journal of transplantation · 2025Article
- Cancer incidence following bariatric surgery in renal transplant recipients: a retrospective multi-center analysis.Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery · 2024Article
- Obesity, organ failure, and transplantation: a review of the role of metabolic and bariatric surgery in transplant candidates and recipients.Surgical endoscopy · 2024Review
- The Impact and Effectiveness of Weight Loss on Kidney Transplant Outcomes: A Narrative Review.Nutrients · 2023Review
- The effect of calcineurin inhibitors on anthropometric measurements in kidney transplant recipients.BMC nephrology · 2022Article
Corrections and comments
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRenal transplantation is the definitive treatment for patients with end-stage renal disease (ESRD). It is associated with better quality of life and patient survival. Nevertheless, these benefits come with rising concerns about weight gain and metabolic abnormalities, which adversely impact transplant outcomes.
objectiveThe objective of this study is to estimate the incidence of weight gain in the first year post-renal transplant in addition to the assessment of potential risk factors and the resulting outcome of the graft.
methodsWe conducted a single-center retrospective cohort study of all 295 patients who underwent kidney transplantation at King Abdulaziz Medical City (KAMC) between January 2016 and December 2019. Clinical and laboratory variables were collected from electronic records. Continuous variables were reported as mean ± standard deviation. Comparison between groups was assessed by unpaired t-test or Mann-Whitney U test while follow-up data were compared using paired t-test and repeated measures ANOVA. Association between the potential risk factors and the weight gain was assessed by means of binary logistic regression analysis.
resultsSignificant weight gain was observed in 161 (54.6%) patients. Females were 119 (40.30%) of the cohort. The mean age was 45.3±15.1 years. The prevalence of diabetes was 234 (79.6%), while hypertensives constituted 77 (26.3%). The comparison between patients who gained weight significantly and patients with stable weight showed a numerical higher prevalence of female gender in patients who had more weight gain (44.1% vs. 35.8%), higher diabetes, higher rate of a living donor, and statistically significant lower dialysis duration before transplant. Other clinical and laboratory variables were comparable between the two groups.
conclusionOur study showed a high incidence of clinically significant weight gain among patients post-renal transplantation. Patients with lower dialysis duration, a living kidney donor and those who are obese at baseline were at higher risk of gaining weight. Patients who underwent kidney transplantation should be monitored closely for weight gain and further studies are needed to determine the risk factors and appropriate interventions.
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