Evidence map›Paper›PMID 35652956›Full record

ArticleJournal of molecular modeling2022

A new quinolinone-chalcone hybrid with potential antibacterial and herbicidal properties using in silico approaches.

Vitor S Duarte, Renata L G Paula, Jean M F Custodio, Giulio D C D'Oliveira, Leonardo L Borges, Caridad N Pérez, Pal Perjesi, Allen G Oliver, Hamilton B Napolitano

Abstract read
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Article in Journal of molecular modeling, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. TheACS omega · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Vitor S DuarteResearch and Energy Efficiency Center, CAOA, Vehicle Assembler LTDA, Anápolis, GO, Brazil. vitor.sduarte@seduc.go.gov.br.
Renata L G PaulaCampus of Exact and Technological Sciences, State University of Goiás, Anápolis, GO, Brazil.
Jean M F CustodioDepartment of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, IN, USA.
Giulio D C D'OliveiraInstitute of Chemistry, Federal University of Goiás, Goiânia, GO, Brazil.
Leonardo L BorgesCampus of Exact and Technological Sciences, State University of Goiás, Anápolis, GO, Brazil.
Caridad N PérezInstitute of Chemistry, Federal University of Goiás, Goiânia, GO, Brazil.
Pal PerjesiLaboratory of New Materials, Evangelical University of Goiás, Anápolis, GO, Brazil.
Allen G OliverDepartment of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, IN, USA.
Hamilton B NapolitanoCampus of Exact and Technological Sciences, State University of Goiás, Anápolis, GO, Brazil. hbnapolitano@gmail.com.ORCID http://orcid.org/0000-0002-6047-9995

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Quinolinone-chalcones are hybrid compounds consisting of chalcone and quinolone moieties with biological activity related to their hybrid structure. This work seeks to describe the structural and theoretical parameters related to the physicochemical properties and biological activity of a new quinolinone-chalcone. The synthesis, structural characterization by X-ray diffraction, molecular topology by Hirshfeld surfaces and QTAIM, molecular electronic calculations, and pharmacophore analysis were described. The weak interactions C-H

Indexed as

ChalconeChalconesHerbicidesQuinolonesAnti-Bacterial AgentsBacterial ProteinsRepressor ProteinsAnti-Bacterial AgentsBacterial ProteinsChalconeChalconesHerbicidesQuinolonesRepressor ProteinsMolecular modelingPotential herbicide activityQTAIM analysisQuinolinone-chalcone

Identifiers

PMID35652956

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.