Evidence map›Paper›PMID 35652954›Full record

ArticleAutophagy2023

Impaired autophagy promotes hair loss in the C3H/HeJ mouse model of alopecia areata.

Rupali Gund, Angela M Christiano

Open access · greenAbstract read
In one paragraph

Article in Autophagy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
5.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Frontiers in pharmacology · 2025
    Article
  6. Review
  7. Review
  8. Pathogenesis of Alopecia Areata and Vitiligo: Commonalities and Differences.International journal of molecular sciences · 2024
    Review
  9. Article
  10. Autophagy Dysfunction: The Kernel of Hair Loss?Clinical, cosmetic and investigational dermatology · 2024
    Review
  11. Review
  12. Review
  13. Review
  14. International journal of molecular sciences · 2023
    Review
  15. Oxidative stress and alopecia areata.Frontiers in medicine · 2023
    Review
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Rupali GundDepartment of Dermatology, Vagelos College of Physicians and Surgeons, Columbia University, New York, New York USA.ORCID 0000-0001-9611-2258
Angela M ChristianoDepartment of Dermatology, Vagelos College of Physicians and Surgeons, Columbia University, New York, New York USA.
Columbia University · US

Funding

Tumor Biology and Microenvironment ProgramP30CA013696 · NCI · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI Anil K Rustgi · 1985 to 2026
$115.3M
Project 1: Translational Science of Alopecia AreataP50AR070588 · NIAMS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI CHRISTIANO, ANGELA M · 2016 to 2021
$8.0M
Translational and Precision Medicine Resources Core (TRAP)P30AR069632 · NIAMS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI OWENS, DAVID M · 2016 to 2020
$3.9M
Becton Dickinson LSR II Analytical Flow CytometerS10RR027050 · NCRR · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI CLYNES, RAPHAEL A. · 2011 to 2011
$413k
NCI NIH HHS P30 CA013696NCRR NIH HHS S10 RR027050NIAMS NIH HHS P30 AR069632NIAMS NIH HHS P50 AR070588
6 · The paper itself

Abstract

Alopecia areata (AA) involves an aberrant immune attack on the hair follicle (HF), which leads to hair loss. Previous genetic data from our lab pointed to a connection between macroautophagy/autophagy and AA pathogenesis, and GWAS identified

Indexed as

Alopecia AreataAnimalsAutophagyDisease Models, AnimalGenome-Wide Association StudyLectins, C-TypeMiceMice, Inbred C3HMonosaccharide Transport ProteinsCLEC16A protein, mouseLectins, C-TypeMonosaccharide Transport ProteinsAutoimmunityBECN1hairinflammationmammalian autophagyMAP1LC3BskinSQSTM1Tat-BECN1T cells

Identifiers

PMID35652954
PMCPMC9809940
OpenAlexW4281709795

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.