Evidence map›Paper›PMID 35652902›Full record

ArticleThe American journal on addictions2022

Gender differences among persons entering medication treatment for opioid use disorder in the community.

Angela Di Paola, Noor Taweh, Breanne E Biondi, Ariadna Forray, Cynthia A Frank, Albert Shaw, Sandra A Springer

Open access · greenAbstract read
In one paragraph

Article in The American journal on addictions, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Angela Di PaolaDepartment of Internal Medicine, Section of Infectious Diseases, AIDS Program, Yale School of Medicine, New Haven, Connecticut, USA.ORCID 0000-0002-9929-7136
Noor TawehDepartment of Internal Medicine, Section of Infectious Diseases, AIDS Program, Yale School of Medicine, New Haven, Connecticut, USA.
Breanne E BiondiDepartment of Health Law, Policy, and Management, Boston University School of Public Health, Boston, Massachusetts, USA.
Ariadna ForrayDepartment of Psychiatry, Yale School of Medicine, New Haven, Connecticut, USA.
Cynthia A FrankDepartment of Internal Medicine, Section of Infectious Diseases, AIDS Program, Yale School of Medicine, New Haven, Connecticut, USA.
Albert ShawDepartment of Internal Medicine, Section of Infectious Diseases, AIDS Program, Yale School of Medicine, New Haven, Connecticut, USA.
Sandra A SpringerDepartment of Internal Medicine, Section of Infectious Diseases, AIDS Program, Yale School of Medicine, New Haven, Connecticut, USA.ORCID 0000-0002-6318-1000
Yale University · USBoston University · USUniversity of Connecticut · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
The Impact of HIV Infection on Immunologic, Transcriptomic, and Metabolomic Signatures of Medication-Assisted Therapy for Opioid AddictionR01DA043337 · NIDA · YALE UNIVERSITY · PI SHAW, ALBERT C, SPRINGER, SANDRA ANN · 2016 to 2020
$5.8M
Evaluating the role of opioid medication assisted therapies in HIV-1 Persistence for persons living with HIV and opioid use disordersR61DA047037 · NIDA · YALE UNIVERSITY · PI HO, YA-CHI, KLUGER, YUVAL · 2018 to 2020
$2.3M
Midcareer Award in Translational Immunology of AgingK24AG042489 · NIA · YALE UNIVERSITY · PI SHAW, ALBERT C · 2012 to 2022
$1.8M
Medication Assisted Therapy as a Conduit to Care for HIV+ CJS Populations TransitK02DA032322 · NIDA · YALE UNIVERSITY · PI SPRINGER, SANDRA ANN · 2011 to 2022
$1.3M
NCATS NIH HHS UL1 TR001863NIA NIH HHS K24 AG042489NIDA NIH HHS K02 DA032322NIDA NIH HHS R01 DA043337
6 · The paper itself

Abstract

BACKGROUND AND

objectivesWe evaluated gender differences among persons initiating medications for opioid use disorder (MOUD).

methodsAnalyses of baseline assessments for a study evaluating the impact of MOUD on outcomes included: demographics, DSM-5 diagnoses, depression severity, quality of life (QoL), and medication history (N = 125).

resultsWhen compared to men, women had a greater prevalence of generalized anxiety and posttraumatic stress disorders; and worse psychological QoL. Women were less likely to be prescribed psychiatric medications. DISCUSSION AND

conclusionsWomen may benefit from tailored multidisciplinary programs with MOUD. SCIENTIFIC SIGNIFICANCE: This study identified that women with OUD seeking MOUD in the community had greater sedative hypnotic nonprescribed medication use and psychiatric comorbidity than men, all of which can contribute to poorer retention on MOUD and higher risk of morbidity and mortality. Thus, concurrent psychiatric disorder screening and treatment integrated with MOUD may improve retention on MOUD, opioid relapse and overdose for women.

Indexed as

BuprenorphineOpioid-Related DisordersAnalgesics, OpioidFemaleHumansMaleNaltrexoneOpiate Substitution TreatmentQuality of LifeSex FactorsAnalgesics, OpioidBuprenorphineNaltrexone

Identifiers

PMID35652902
PMCPMC9463117
OpenAlexW4281731955

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.