Evidence map›Paper›PMID 35652836›Full record

ArticleJournal of cardiovascular electrophysiology2022

A comparison of clinical outcomes and cost of radiofrequency catheter ablation for atrial fibrillation with monitored anesthesia care versus general anesthesia.

Miki Yokokawa, Aman Chugh, Anna Dubovoy, Milo Engoren, Krit Jongnarangsin, Rakesh Latchamsetty, Hamid Ghanbari, Mohammed Saeed, Ryan Cunnane, Thomas Crawford and 10 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of cardiovascular electrophysiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Sedation vs. general anaesthesia in patients with atrial fibrillation undergoing catheter ablation: a systematic review and meta-analysis.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025
    Pooled it
  2. Sedation strategies for pulsed-field ablation of atrial fibrillation: focus on deep sedation with intravenous ketamine in spontaneous respiration.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2023
    Trial
  3. Article
  4. Anaesthetic Techniques for Cardiac Ablation-A Scoping Review.Acta anaesthesiologica Scandinavica · 2026
    Article
  5. Article
  6. Feasibility of deep sedation for catheter ablation of atrial fibrillation using pulsed field ablation.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2025
    Article
  7. Article
  8. Optimal anesthesia approach during catheter ablation of premature ventricular complexes: you snooze, you lose!Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2023
    Article
  9. Review
  10. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

20 authors at 1 institution in 1 country.

Miki YokokawaCardiac Arrhythmia Service, University of Michigan, Ann Arbor, Michigan, USA.ORCID 0000-0002-1879-4131
Aman ChughCardiac Arrhythmia Service, University of Michigan, Ann Arbor, Michigan, USA.
Anna DubovoyCardiac Anesthesiology, University of Michigan, Ann Arbor, Michigan, USA.
Milo EngorenCardiac Anesthesiology, University of Michigan, Ann Arbor, Michigan, USA.
Krit JongnarangsinCardiac Arrhythmia Service, University of Michigan, Ann Arbor, Michigan, USA.
Rakesh LatchamsettyCardiac Arrhythmia Service, University of Michigan, Ann Arbor, Michigan, USA.
Hamid GhanbariCardiac Arrhythmia Service, University of Michigan, Ann Arbor, Michigan, USA.
Mohammed SaeedCardiac Arrhythmia Service, University of Michigan, Ann Arbor, Michigan, USA.
Ryan CunnaneCardiac Arrhythmia Service, University of Michigan, Ann Arbor, Michigan, USA.
Thomas CrawfordCardiac Arrhythmia Service, University of Michigan, Ann Arbor, Michigan, USA.
Michael GhannamCardiac Arrhythmia Service, University of Michigan, Ann Arbor, Michigan, USA.ORCID 0000-0001-6951-5238
Jackson LiangCardiac Arrhythmia Service, University of Michigan, Ann Arbor, Michigan, USA.ORCID 0000-0001-8608-8899
Robert KeastCardiac Arrhythmia Service, University of Michigan, Ann Arbor, Michigan, USA.
David KarpenkoCardiac Arrhythmia Service, University of Michigan, Ann Arbor, Michigan, USA.
Frank BogunCardiac Arrhythmia Service, University of Michigan, Ann Arbor, Michigan, USA.ORCID 0000-0002-0391-7282
Frank PelosiCardiac Arrhythmia Service, University of Michigan, Ann Arbor, Michigan, USA.ORCID 0000-0003-0889-9287
Timur DubovoyCardiac Anesthesiology, University of Michigan, Ann Arbor, Michigan, USA.
Mathew CaldwellCardiac Anesthesiology, University of Michigan, Ann Arbor, Michigan, USA.
Fred MoradyCardiac Arrhythmia Service, University of Michigan, Ann Arbor, Michigan, USA.
Hakan OralCardiac Arrhythmia Service, University of Michigan, Ann Arbor, Michigan, USA.ORCID 0000-0002-2237-0155
University of Michigan · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionMonitored anesthesia care (MAC) or general anesthesia (GA) can be used during catheter ablation (CA) of atrial fibrillation (AF). However, each approach may have advantages and disadvantages with variability in operator preferences. The optimal approach has not been well established. The purpose of this study was to compare procedural efficacy, safety, clinical outcomes, and cost of CA for AF performed with MAC versus GA.

methodsThe study population consisted of 810 consecutive patients (mean age: 63 ± 10 years, paroxysmal AF: 48%) who underwent a first CA for AF. All patients completed a preprocedural evaluation by the anesthesiologists. Among the 810 patients, MAC was used in 534 (66%) and GA in 276 (34%). Ten patients (1.5%) had to convert to GA during the CA.

resultsAlthough the total anesthesia care was longer with GA particularly in patients with persistent AF, CA was shorter by 5 min with GA than MAC (p < 0.01). Prevalence of perioperative complications was similar between the two groups (4% vs. 4%, p = 0.89). There was no atrioesophageal fistula with either approach. GA was associated with a small, ~7% increase in total charges due to longer anesthesia care. During 43 ± 17 months of follow-up after a single ablation procedure, 271/534 patients (51%) in the MAC and 129/276 (47%) patients in the GA groups were in sinus rhythm without concomitant antiarrhythmic drug therapy (p = 0.28).

conclusionWith the participation of an anesthesiologist, and proper preoperative assessment, CA of AF using GA or MAC has similar efficacy and safety.

Indexed as

Atrial FibrillationCatheter AblationAgedAnesthesia, GeneralAnti-Arrhythmia AgentsHumansMiddle AgedTreatment OutcomeAnti-Arrhythmia Agentsatrial fibrillationcatheter ablationgeneral anesthesiamonitored anesthesia care

Identifiers

PMID35652836
PMCPMC9541425
OpenAlexW4281898068

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.