ArticleJournal of the American Chemical Society2022
A Photo-responsive Transmembrane Anion Transporter Relay.
Article in Journal of the American Chemical Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
29 citing papers in PubMed, 94 citations in OpenAlex.
- Light-Enhanced Chloride Transport by Thiourea-Appended Molecular Motor.Angewandte Chemie (International ed. in English) · 2026Article
- Visible-Light Sensitized Isomerization in the Lipid Bilayer Enables Activation of a Transmembrane Transporter.Angewandte Chemie (International ed. in English) · 2026Article
- A Versatile Strategy for Light-Driven Active Transport of Ions.Angewandte Chemie (International ed. in English) · 2026Article
- Medical and Nonmedical Applications of Synthetic Transmembrane Anion Transporters.Chemical reviews · 2025Review
- Resonsive anion transport with a Hamilton receptor-based anionophore controlled by photo-activation and host-guest competitive inhibition.Chemical science · 2025Article
- A controllable photoresponsive potassium transporter.Nature communications · 2025Article
- Manipulation of Chemistry and Biology with Visible Light Using Tetra-ortho-Substituted Azobenzenes and Azonium Ions.Angewandte Chemie (International ed. in English) · 2025Review
- Rapid Water Permeation by Aramid Foldamer Nanochannels With Hydrophobic Interiors.Angewandte Chemie (International ed. in English) · 2025Article
- Tailoring Polymer Coatings and Grafting Structures for Photoswitchable Ionic Transport in Solid-State Nanochannels.Chemistry, an Asian journal · 2025Article
- ON-OFF nanopores for optical control of transmembrane ionic communication.Nature nanotechnology · 2025Article
- Anion Transport by Bambusuril-Bile Acid Conjugates: Drastic Effect of the Cholesterol Content.Angewandte Chemie (International ed. in English) · 2025Article
- Glucose-derived receptors for photo-controlled binding of amino acid esters in water.Communications chemistry · 2025Article
- Photoswitchable phospholipids for the optical control of membrane processes, protein function, and drug delivery.Communications materials · 2025Review
- Off-On Photo- and Redox-Triggered Anion Transport Using an Indole-Based Hydrogen Bond Switch.ACS omega · 2024Article
- Highly Selective Artificial KJACS Au · 2024Article
- Article
- Rectifying artificial nanochannels with multiple interconvertible permeability states.Nature communications · 2024Article
- Multiple control of azoquinoline based molecular photoswitches.Chemical science · 2024Article
- Molecular Machines For The Control Of Transmembrane Transport.Journal of the American Chemical Society · 2023Review
- Photocontrolled activation of doublyChemical science · 2023Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ion transport across lipid membranes in biology is controlled by stimuli-responsive membrane channels and molecular machine ion pumps such as ATPases. Here, we report a synthetic molecular machine-like ion transport relay, in which transporters on opposite sides of a lipid bilayer membrane facilitate transport by passing ions between them. By incorporating a photo-responsive telescopic arm into the relay design, this process is reversibly controlled in response to irradiation with blue and green light. Transport occurs only in the extended state when the length of the arm is sufficient to pass the anion between transporters located on opposite sides of the membrane. In contrast, the contracted state of the telescopic arm is too short to mediate effective transport. The system acts as a stimuli-responsive ensemble of machine-like components, reminiscent of robotic arms in a factory assembly line, working cooperatively to mediate ion transport. This work points to new prospects for using lipid bilayer membranes as scaffolds for confining, orientating, and controlling the relative positions of molecular machines, thus enabling multiple components to work in concert and opening up new applications in biological contexts.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.