ArticleMicrobiology spectrum2022
Isolation and Identification of Two Clinical Strains of the Novel Genotype
Article in Microbiology spectrum, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
11 citing papers in PubMed, 10 citations in OpenAlex.
- Carboxypeptidase A6 contributes to bovine enterovirus F production through apoptosis-associated PI3K/AKT/FOXO1 signaling.Virulence · 2026Article
- Isolation and partial 5'UTR-based molecular characterization of bovine enterovirus F from non-diarrheic cattle in Türkiye.Molecular biology reports · 2026Article
- Construction of a reverse genetics and fluorescent reporter system for a bovine enterovirus isolated from cattle with diarrhea.BMC veterinary research · 2026Article
- Isolation and identification of a genotype F bovine enterovirus in western China.Microbiology spectrum · 2026Article
- Detection and molecular characterization of bovine enterovirus E2 from dairy calves with respiratory disease in Urumqi, Xinjiang, China.Frontiers in cellular and infection microbiology · 2026Article
- Characterization and Evolutionary Analysis of Type E4 Bovine Enterovirus From Clinical Cattle With Diarrhea in Inner Mongolia, China.Transboundary and emerging diseases · 2026Article
- Enterovirus E infections in goats with respiratory disease.BMC veterinary research · 2025Article
- Epidemiological survey of calf diarrhea related viruses in several areas of Guangdong Province.Frontiers in microbiology · 2024Article
- VIGA: a one-stop tool for eukaryotic virus identification and genome assembly from next-generation-sequencing data.Briefings in bioinformatics · 2023Article
- Establishment and application of multiplex droplet digital polymerase chain reaction assay for bovine enterovirus, bovine coronavirus, and bovine rotavirus.Frontiers in veterinary science · 2023Article
- Antiviral Effect of Bovine Lactoferrin against Enterovirus E.Molecules (Basel, Switzerland) · 2022Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Most enterovirus (EV) infections are subclinical but, occasionally, can cause severe and potentially fatal diseases in humans and animals. Currently, EVs are divided into 12 types (A to L) based on phylogenetic analysis and on their natural hosts. Bovine enterovirus (BEV) is an essential member of the enterovirus belonging to the types E and F that attacks cattle as its natural host and causes clinical disorders in the digestive, respiratory, and reproductive tracts. In 2020, several dairy farms in China experienced cow mortality with acute clinical signs, including fever, and diarrhea. In these cases, GX20-1 and JS20-1 virus strains were isolated and sequenced. Cellular adaptation of these two strains showed efficient replications on Madin-Darby bovine kidney (MDBK) cells and produced a significant cytopathogenic effect (CPE). However, on baby hamster kidney (BHK-21) and Vero cells, viral replication was inefficient and did not produce CPE. As noted in comparative genomics analysis, these two strains showed distant evolutionary relationships with the well-known E1 to E4 and F1 to F4 subtypes of BEV and high sequence identities with the candidate type
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