Evidence map›Paper›PMID 35652624›Full record

ArticleJournal of diabetes science and technology2022

Trimetazidine Blocks Lipid Oxidation-Should it be Repurposed for Prevention and Treatment of Diabetic Ketoacidosis?

David C Klonoff, Nicole Y Xu, Kevin T Nguyen, David Kerr, Chhavi Mehta, Guillermo E Umpierrez, George A Brooks

Open access · bronzeAbstract readEditorial
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of diabetes science and technology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

David C KlonoffDiabetes Research Institute, Mills-Peninsula Medical Center, San Mateo, CA, USA.ORCID 0000-0001-6394-6862
Nicole Y XuDiabetes Technology Society, Burlingame, CA, USA.ORCID 0000-0001-9353-8819
Kevin T NguyenDiabetes Technology Society, Burlingame, CA, USA.ORCID 0000-0001-9102-6537
David KerrSansum Diabetes Research Institute, Santa Barbara, CA, USA.ORCID 0000-0003-1335-1857
Chhavi MehtaPalo Alto Foundation Medical Group, Burlingame, CA, USA.ORCID 0000-0003-0223-5009
Guillermo E UmpierrezEmory University, Atlanta, GA, USA.ORCID 0000-0002-3252-5026
George A BrooksIntegrative Biology, University of California, Berkeley, Berkeley, CA, USA.ORCID 0000-0002-1389-1629
Diabetes Technology Society · USEmory University · USMills Peninsula Health Services · USSansum Diabetes Research Institute · USUniversity of California, Berkeley · US

Funding

Aging Mitochondrial Fragmentation and Metabolic InflexibilityR01AG059715 · NIA · UNIVERSITY OF CALIFORNIA BERKELEY · PI BROOKS, GEORGE AUSTIN · 2018 to 2022
$3.0M
NIA NIH HHS R01 AG059715
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Diabetes MellitusDiabetic KetoacidosisTrimetazidineBlood GlucoseHumansLipidsBlood GlucoseLipidsTrimetazidineketoacidosismetabolic modulatorrepurposeSGLT2 inhibitortrimetazidine

Identifiers

PMID35652624
PMCPMC9445353
OpenAlexW4281618910

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.