Evidence map›Paper›PMID 35652591›Full record

ArticlemBio2022

Epithelial and Neutrophil Interactions and Coordinated Response to

Jose M Lemme-Dumit, Michele Doucet, Nicholas C Zachos, Marcela F Pasetti

Open access · goldAbstract read
In one paragraph

Article in mBio, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 27 citations in OpenAlex.

  1. Multifunctional antibody responses from a primateScience translational medicine · 2026
    Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. Oral immunization withmSphere · 2024
    Article
  11. Article
  12. Recent Advances in Cell-Based In Vitro Models to Recreate Human Intestinal Inflammation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
    Review
  13. Co-culturing Human Intestinal Enteroid Monolayers with Innate Immune Cells.Methods in molecular biology (Clifton, N.J.) · 2023
    Article
  14. Functional assays to evaluate antibody-mediated responses againstFrontiers in cellular and infection microbiology · 2023
    Review
  15. Evaluation of a Live AttenuatedPathogens (Basel, Switzerland) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Jose M Lemme-DumitDepartment of Pediatrics, Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Michele DoucetDepartment of Medicine, Division of Gastroenterology and Hepatology, Johns Hopkins University School of Medicinegrid.471401.7, Baltimore, Maryland, USA.
Nicholas C ZachosDepartment of Medicine, Division of Gastroenterology and Hepatology, Johns Hopkins University School of Medicinegrid.471401.7, Baltimore, Maryland, USA.
Marcela F PasettiDepartment of Pediatrics, Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Johns Hopkins Medicine · USUniversity of Maryland, Baltimore · US

Funding

UNIVERSITY OF MARYLAND GREENEBAUM CANCER CENTERSUPPORT GRANTP30CA134274 · NCI · UNIVERSITY OF MARYLAND BALTIMORE · PI Vu H. Duong · 2008 to 2026
$51.0M
Project 3 - Human colonoids as a model for the pathobiology of EHECP01AI125181 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI FOULKE-ABEL, JENNIFER, KAPER, JAMES B · 2016 to 2025
$18.6M
Translational Research Enhancement CoreP30DK089502 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI ZACHOS, NICHOLAS CONSTANTINE · 2011 to 2020
$12.0M
Serological assays to predict Shigella vaccine efficacyR01AI125841 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI PASETTI, MARCELA F · 2016 to 2020
$2.8M
Vaccines and maternally acquired immunity to prevent shigellosis in childrenR01AI117734 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI PASETTI, MARCELA F · 2015 to 2019
$2.0M
Advanced components for an existing spinning disk confocal in an established core imaging facilityS10OD026698 · OD · UNIVERSITY OF MARYLAND BALTIMORE · PI BLANPIED, THOMAS A · 2019 to 2019
$274k
NCI NIH HHS P30 CA134274NIAID NIH HHS P01 AI125181NIAID NIH HHS R01 AI117734NIAID NIH HHS R01 AI125841NIDDK NIH HHS P30 DK089502NIH HHS S10 OD026698
6 · The paper itself

Abstract

Polymorphonuclear neutrophils (PMN) are recruited to the gastrointestinal mucosa in response to inflammation, injury, and infection. Here, we report the development and the characterization of an

Indexed as

Dysentery, BacillaryShigellaAnimalsCells, CulturedChild, PreschoolCoculture TechniquesEpithelial CellsHumansInterleukin-8Intestinal MucosaNeutrophilsInterleukin-8enteroidepithelial cellshost-pathogen interactionshumaninnate immunityintestinal mucosaneutrophilsShigella

Identifiers

PMID35652591
PMCPMC9239269
OpenAlexW4281862343

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.